Pătru Simona, Pădureanu Rodica, Dumitrescu Florentina, Pădureanu Vlad, Rădulescu Dumitru, Dragoi Diana, Matei Daniela
Department of Physical and Rehabilitation Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Department of Biochemistry, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Exp Ther Med. 2021 May;21(5):528. doi: 10.3892/etm.2021.9960. Epub 2021 Mar 22.
There is no specific cure for fibromyalgia (FM), but combined non-pharmacologic and pharmacologic treatments may mitigate symptoms and improve quality of life in patients. The aim of the present study was to monitor patient response to several types of therapy, including cognitive-behavioral and occupational therapy, and kinetic therapy, as compared to a control group that was not subjected to any form of therapy. The study included 98 FM patients, all women, out of which 32 received cognitive-behavioral therapy and occupational therapy (CBT+OT), 34 kinetic therapy (KT) and 32 participated as controls. The evaluation protocol comprised two questionnaires developed in order to assess the patient's condition as fully as possible: Fibromyalgia Impact Questionnaire (FIQ) and Fibro Fatigue (FF) scale. At the pre-evaluation there were no significant inter-group differences. At post-evaluation significant differences were observed between the control sample and the group subjected to kinetic therapy (P<0.05). FIQ scores decreased in the CBT+OT group too, but less than that in the KT group. The FF scale registered notable evolutions in time for the group subjected to kinetic therapy. In order to control and improve most of the FM symptoms, besides proper medication, we suggest an interdisciplinary intervention mainly focusing on long-term individualized kinetic therapy. The simultaneous integration of a cognitive-behavioural and occupational therapy intervention could be the element that completes the complex treatment of FM patients.
纤维肌痛（FM）尚无特效疗法，但非药物和药物联合治疗可减轻患者症状并提高生活质量。本研究旨在监测患者对多种治疗方法的反应，包括认知行为疗法、职业疗法和运动疗法，并与未接受任何形式治疗的对照组进行比较。该研究纳入了98名FM患者，均为女性，其中32人接受认知行为疗法和职业疗法（CBT+OT），34人接受运动疗法（KT），32人作为对照组。评估方案包括两份专门设计的问卷，以尽可能全面地评估患者状况：纤维肌痛影响问卷（FIQ）和纤维肌痛疲劳（FF）量表。评估前，组间无显著差异。评估后，观察到对照组与接受运动疗法的组之间存在显著差异（P<0.05）。CBT+OT组的FIQ评分也有所下降，但低于KT组。FF量表显示接受运动疗法的组随时间有显著变化。为了控制和改善大多数FM症状，除了适当用药外，我们建议采取跨学科干预措施，主要侧重于长期个性化运动疗法。同时结合认知行为和职业疗法干预可能是完善FM患者综合治疗的要素。
