Lee Steven J, Rabinovich Remy V, Kim Andrew
Department of Orthopaedic Surgery, Nicholas Institute of Sports Medicine and Athletic Trauma (NISMAT), Lenox Hill Hospital, New York, New York.
Department of Orthopaedic Surgery, Lenox Hill Hospital, New York, New York.
J Wrist Surg. 2021 Apr;10(2):116-122. doi: 10.1055/s-0040-1718912. Epub 2020 Oct 29.
The purpose of this study was to evaluate the short-term outcomes of patients undergoing proximal row carpectomy (PRC) with interposition arthroplasty using a decellularized dermal allograft. Patients with a minimum of 1-year follow-up after undergoing a PRC using decellularized dermal allograft were contacted for clinical evaluation, radiographs, and postoperative outcome questionnaires, including the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire as well as the modified Likert scale for patient satisfaction. Nine of ten (90%) consecutive patients who were treated using this surgical technique were available for follow-up. At a mean follow-up of 18 months, a total of nine patients achieved a mean flexion-extension arc of 113 degrees, pronosupination of 170.5 degrees, grip strength of 68 Ibs and pinch strength of 17 Ibs. Relative to the contralateral side, these values were 95, 100, 84 and 82%, respectively. There was significant improvement in the mean DASH score from 63.5 preoperatively to 23.8 postoperatively. Patient satisfaction postoperatively achieved a mean modified Likert score of 1.5. There was no evidence of radiocarpal joint space degeneration or dislocation in any of the patients. No patient suffered wound-related issues, foreign-body reaction to the graft, or other complications. PRC with interposition arthroplasty using a decellularized dermal allograft in patients with degenerative changes at the lunate fossa or capitate demonstrates short-term outcomes comparable to what has been reported for routine PRC in patients without degenerative changes affecting the radiocapitate joint. This method of interposition arthroplasty expands the indications for PRC and may help avoid salvage, motion-sacrificing procedures in select patients with late-stage wrist arthritis. This is a level IV, therapeutic study.
本研究的目的是评估采用脱细胞真皮同种异体移植物进行间置关节成形术的近排腕骨切除术(PRC)患者的短期疗效。对接受使用脱细胞真皮同种异体移植物的PRC术后至少随访1年的患者进行临床评估、影像学检查及术后结果问卷调查,包括上肢、肩部和手部功能障碍(DASH)问卷以及患者满意度改良Likert量表。连续接受该手术技术治疗的10例患者中有9例(90%)可供随访。
平均随访18个月时,9例患者的平均屈伸弧为113度,旋前旋后为170.5度,握力为68磅,捏力为17磅。相对于对侧,这些值分别为95%、100%、84%和82%。平均DASH评分从术前的63.5显著改善至术后的23.8。患者术后满意度的平均改良Likert评分为1.5。所有患者均未出现桡腕关节间隙退变或脱位的迹象。没有患者出现伤口相关问题、对移植物的异物反应或其他并发症。
对于月骨窝或头状骨有退变改变的患者,采用脱细胞真皮同种异体移植物进行间置关节成形术的PRC的短期疗效与报道的无影响桡头关节退变改变的患者进行常规PRC的疗效相当。这种间置关节成形术方法扩大了PRC的适应证,可能有助于避免对部分晚期腕关节炎患者进行挽救性、牺牲活动的手术。
这是一项IV级治疗性研究。