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严重急性呼吸综合征冠状病毒2(SARS-CoV-2)时代传染病的管理趋势:基于2019冠状病毒病(COVID-19)与流感的病理生理比较

Trends in the management of infectious disease under SARS-CoV-2 era: From pathophysiological comparison of COVID-19 and influenza.

作者信息

Seki Masafumi

机构信息

Division of Infectious Diseases and Infection Control, Tohoku Medical and Pharmaceutical University, Miyagi 983-8536, Japan.

出版信息

World J Virol. 2021 Mar 25;10(2):62-68. doi: 10.5501/wjv.v10.i2.62.

DOI:10.5501/wjv.v10.i2.62
PMID:33816151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7995412/
Abstract

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), has become a historic pandemic, and dealing with it is one of the most important aspects of infectious disease treatment today. SARS-CoV-2 has been found to have characteristic and powerful infectivity (ability to propagate) and lethality (severity). With influenza, primary influenza pneumonia from the virus itself is known to exist in addition to secondary bacterial pneumonia. With COVID-19, on the other hand, it is important to provide diagnosis and treatment while keeping acute respiratory distress syndrome and pulmonary edema (alveolar flood) from a similar cytokine storm, as well as severe angiopathy, in mind. The importance of complying with hand hygiene and masks in infection control remains the same as in previous general infection control measures and responses to influenza virus infections and others, but in the future, vaccination will likely be the key to infection control in the community.

摘要

感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)会导致2019冠状病毒病(COVID-19),这已成为一场历史性的大流行,应对它是当今传染病治疗最重要的方面之一。已发现SARS-CoV-2具有独特且强大的传染性(传播能力)和致死性(严重性)。对于流感,除了继发性细菌性肺炎外,已知还存在由病毒本身引起的原发性流感肺炎。另一方面,对于COVID-19,在进行诊断和治疗时,重要的是要考虑到类似细胞因子风暴引发的急性呼吸窘迫综合征和肺水肿(肺泡积水)以及严重血管病变。在感染控制方面,遵守手部卫生和佩戴口罩的重要性与以往一般感染控制措施以及对流感病毒感染等的应对措施相同,但未来,接种疫苗可能是社区感染控制的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75de/7995412/53f1d82f28a6/WJV-10-62-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75de/7995412/e57c414c8abf/WJV-10-62-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75de/7995412/53f1d82f28a6/WJV-10-62-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75de/7995412/e57c414c8abf/WJV-10-62-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75de/7995412/53f1d82f28a6/WJV-10-62-g002.jpg

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