Ukrainets R V, Korneva Yu S
Smolensk State Medical University, Smolensk, Russia.
Smolensk Regional Institute of Pathology, Smolensk, Russia.
Urologiia. 2021 Mar(1):126-130.
The article describes such fundamental and applied aspects of pathogenesis and clinical manifestations of such rare disease as endometriosis of ureters. Frequent involvement of left ureter in its pelvic part, close to distal colon, associated with its inflammatory diseases followed by leaky gut syndrome with bacterial spread to the fallopian tube causing its inflammation and dysfunction, provoking menstrual reflux and predisposing to affection of left ovary, peritoneum and contact spread of endometriosis to ureteral wall. This mechanism fits to the regurgitation theory of endometriosis. Surgery is the gold standard for endometriosis treatment and more beneficial, comparing with conservative treatment and essential for prevention of such dangerous complications as hydronephrosis and renal failure. But the early and in-time diagnostic of endometriosis depend on gynecologists, not urologist, that characterizes endometriosis as significant interdisciplinary problem. In the article symptoms, that must cause concern for this rare pathology are thoroughly described.
本文描述了输尿管子宫内膜异位症这种罕见疾病的发病机制和临床表现的基础及应用方面。左侧输尿管盆腔段常受累,靠近远端结肠,与其炎症性疾病相关,继之以肠漏综合征,细菌扩散至输卵管导致其炎症和功能障碍,引发月经反流,易导致左侧卵巢、腹膜受影响,子宫内膜异位症通过接触蔓延至输尿管壁。这一机制符合子宫内膜异位症的反流理论。手术是子宫内膜异位症治疗的金标准,与保守治疗相比更有益,对于预防肾积水和肾衰竭等危险并发症至关重要。但子宫内膜异位症的早期及时诊断依赖妇科医生而非泌尿科医生,这表明子宫内膜异位症是一个重要的跨学科问题。本文详细描述了这种罕见病症必须引起关注的症状。