Faculty of Computers and Artificial Intelligence, Helwan University, Cairo, Egypt.
Faculty of Engineering and Technology, Badr University in Cairo (BUC), Cairo, Egypt.
J Med Internet Res. 2021 Apr 28;23(4):e23446. doi: 10.2196/23446.
With the growing stress on hospitals caused by the COVID-19 pandemic, the need for home-based solutions has become a necessity to support these overwhelmed hospitals.
The goal of this study was to compare two nonpharmacological respiratory treatment methods for home-isolated COVID-19 patients using a newly developed telemanagement health care system.
In this single-blinded randomized clinical trial, 60 patients with stage 1 pneumonia caused by SARS-CoV-2 infection were treated. Group A (n=30) received oxygen therapy with bilevel positive airway pressure (BiPAP) ventilation, and Group B (n=30) received osteopathic manipulative respiratory and physical therapy techniques. Arterial blood gases of PaO and PaCO, pH, vital signs (ie, temperature, respiratory rate, oxygen saturation, heart rate, and blood pressure), and chest computed tomography scans were used for follow-up and for assessment of the course and duration of recovery.
Analysis of the results showed a significant difference between the two groups (P<.05), with Group A showing shorter recovery periods than Group B (mean 14.9, SD 1.7 days, and mean 23.9, SD 2.3 days, respectively). Significant differences were also observed between baseline and final readings in all of the outcome measures in both groups (P<.05). Regarding posttreatment satisfaction with our proposed telemanagement health care system, positive responses were given by most of the patients in both groups.
It was found that home-based oxygen therapy with BiPAP can be a more effective prophylactic treatment approach than osteopathic manipulative respiratory and physical therapy techniques, as it can impede exacerbation of early-stage COVID-19 pneumonia. Telemanagement health care systems are promising methods to help in the pandemic-related shortage of hospital beds, as they showed reasonable effectiveness and reliability in the monitoring and management of patients with early-stage COVID-19 pneumonia.
ClinicalTrials.gov NCT04368923; https://clinicaltrials.gov/ct2/show/NCT04368923.
由于 COVID-19 大流行给医院带来的压力越来越大，因此需要基于家庭的解决方案来支持这些不堪重负的医院。
本研究的目的是使用新开发的远程医疗保健系统比较两种针对在家隔离的 COVID-19 患者的非药物性呼吸治疗方法。
在这项单盲随机临床试验中，对 60 名因 SARS-CoV-2 感染引起的 1 期肺炎患者进行了治疗。A 组（n=30）接受双水平正压通气（BiPAP）氧疗，B 组（n=30）接受整骨疗法呼吸和物理治疗技术。使用动脉血气 PaO 和 PaCO、pH 值、生命体征（即体温、呼吸频率、血氧饱和度、心率和血压）和胸部计算机断层扫描（CT）进行随访，以评估病程和恢复时间。
分析结果显示两组之间存在显著差异（P<.05），A 组的恢复时间短于 B 组（分别为 14.9，SD 1.7 天和 23.9，SD 2.3 天）。两组所有结果指标的基线和最终读数之间也存在显著差异（P<.05）。关于我们提出的远程医疗保健系统的治疗后满意度，两组中的大多数患者都给出了积极的回应。
结果发现，与整骨疗法呼吸和物理治疗技术相比，在家中使用 BiPAP 进行氧疗可能是一种更有效的预防治疗方法，因为它可以阻止早期 COVID-19 肺炎的恶化。远程医疗保健系统是一种有前途的方法，可以帮助缓解与大流行相关的医院床位短缺问题，因为它们在监测和管理早期 COVID-19 肺炎患者方面表现出了合理的有效性和可靠性。
ClinicalTrials.gov NCT04368923；https://clinicaltrials.gov/ct2/show/NCT04368923。
