Marseille University, Faculté de Médecine - Secteur Timone, EA 3279: CEReSS - Centre d'Étude et de Recherche sur les Services de Santé et la Qualité de vie, Hôpital La Conception, Assistance Publique des Hôpitaux de Marseille, 27, boulevard Jean-Moulin, 13005 Marseille, France.
Nightingale Hospitals-Paris, Clinique du Château de Garches, 11bis, rue de la Porte-Jaune, 92380 Garches, France; Service Hospitalo-Universitaire, CH Sainte Anne, 1, Rue Cabanis, 75014 Paris, France.
Encephale. 2022 Feb;48(1):102-104. doi: 10.1016/j.encep.2021.02.002. Epub 2021 Mar 14.
Psychiatric patients are at risk of hypovitaminosis D and Covid-19-related mortality. In addition to the mental health benefits, vitamin D supplementation may be potentially effective in preventing severe forms of Covid-19 infections. Vitamin D supplementation is not necessary and is not reimbursed in France for this indication. A monthly supplementation of 50,000 IU may be sufficient in most cases. Double the dose is recommended for obese patients. The risk of renal lithiasis is not increased at these doses, even when supplemented in a patient without vitamin D deficiency. The Covid-19 crisis is an opportunity to disseminate vitamin D supplementation in psychiatric patients, as it has been shown to be effective in other respiratory diseases such as mild upper respiratory tract infections and influenza.
精神疾病患者有患维生素 D 缺乏症和与 COVID-19 相关的死亡率的风险。除了对心理健康有好处外，维生素 D 补充剂可能对预防 COVID-19 感染的严重形式有效。在法国，维生素 D 补充剂不是必需的，也没有为此适应症报销。在大多数情况下，每月补充 50000IU 可能就足够了。对于肥胖患者，建议加倍剂量。即使在没有维生素 D 缺乏的患者中补充，这些剂量也不会增加肾结石的风险。COVID-19 危机为在精神疾病患者中传播维生素 D 补充剂提供了机会，因为它在其他呼吸道疾病（如轻度上呼吸道感染和流感）中已被证明有效。
