Division of Pulmonary Medicine, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Pediatr Pulmonol. 2021 Jul;56(7):1857-1867. doi: 10.1002/ppul.25384. Epub 2021 Apr 5.
Use of electronic nicotine delivery systems (ENDS), also known as e-cigarettes, in the adolescent population has significantly increased over the past several years. This rise led to an outbreak of e-cigarette or vaping product use-associated lung injury (EVALI) in the summer of 2019. Since that time, numerous case reports and case series on vaping and EVALI have been published but the majority of literature highlights the adult population with few articles focusing on pediatric patients. Given the addictive nature of these products and the lack of full understanding of the human health effects, there is concern that use of ENDS may have lasting impacts on users, especially adolescents and young adults. The goal of this review is to critically assess published data on ENDS use in children, report our institutional experience, discuss the reasons why the use of ENDS have increased among young individuals, outline the current understanding of EVALI as it pertains to the pediatric population, and discuss future opportunities for health policy implementation.
在过去的几年中，青少年人群中使用电子尼古丁输送系统（ENDS），也称为电子烟，显著增加。这一增长导致 2019 年夏季爆发了电子烟或蒸气产品使用相关的肺损伤（EVALI）。从那时起，已经发表了许多关于电子烟和 EVALI 的病例报告和病例系列，但大多数文献都强调了成年人群，很少有文章关注儿科患者。鉴于这些产品具有成瘾性，并且对人类健康影响的了解还不全面，人们担心使用 ENDS 可能会对使用者，尤其是青少年和年轻人产生持久影响。本综述的目的是批判性地评估已发表的关于儿童使用 ENDS 的数据，报告我们机构的经验，讨论年轻人中使用 ENDS 增加的原因，概述目前对与儿科人群相关的 EVALI 的理解，并讨论实施卫生政策的未来机会。
