Asakura K, Nishio M
Dept. of Otolaryngology, Sapporo Medical College.
Gan To Kagaku Ryoho. 1988 Apr;15(4 Pt 2-2):1313-7.
We performed a clinical study on 128 patients with squamous cell carcinoma of maxillary sinus who were treated at Sapporo Medical College (SMC) and National Sapporo Hospital (NSH) from 1977 to 1985. All patients were treated with the combination of external irradiation, surgery and intra-arterial infusion of anti-cancer drugs. Each patient was grouped according to the variation of surgical treatment. Final local tumor control rate was the best in the group of patients undergoing radical operation or thorough tumor reduction surgery in each hospital (68% in group C in SMC and 62% in reduction surgical level 3 in NSH). No patients with a residual tumor after primary treatment were salvaged by any secondary treatment. Eleven out of 30 patients with a local tumor recurrence were salvaged by the second treatment. The salvage rate in the patients with a minor recurrence which might be resected by minor surgery was better than with a major recurrence which might be treated by a wide resection (80% and 28%, respectively). 3 patients with a local recurrence were treated by the combination of the surgery and brachytherapy, and encouraging results were obtained in these patients.