Tada M, Karita M, Yanai H, Takemoto T
First Dept. of Internal Medicine, Yamaguchi University School of Medicine.
Gan To Kagaku Ryoho. 1988 Apr;15(4 Pt 2-3):1460-5.
Strip biopsy is carried out in accordance with the principle of endoscopic injection and polypectomy. By using strip biopsy, the full thickness of the mucosa is removed, including the submucosal layer, largely without risk, even in cases of depressed or flat lesions. We have applied this procedure to the therapy of early gastric cancer. Its most valuable aspect is that the resected tissue is collected and the efficacy of the therapy can be evaluated from both macroscopic findings and histological sections. We have applied strip biopsy in 133 cases involving 137 lesions of 8 early gastric cancer, of which 65.0% were totally resected using only the strip biopsy technique. Other cases were treated surgically or subjected to additional endoscopic therapy. sixteen cases were confirmed to have been perfected resected by stomach surgery. Another 71 patients who were not candidates for surgery because of their physical condition have been followed endoscopically for 2 to 48 months, but there has not been any recurrence. On the basis of this study, we believe that the strip biopsy therapy of early gastric cancer should be evaluated in addition to surgical therapy, especially in cases of small lesions localized only in the mucosa.
条形活检是按照内镜注射和息肉切除术的原则进行的。通过条形活检，可切除包括黏膜下层在内的全层黏膜，即使在凹陷或扁平病变的情况下，也基本没有风险。我们已将此方法应用于早期胃癌的治疗。其最有价值的方面在于，切除的组织被收集起来，并且可以从宏观发现和组织学切片两方面评估治疗效果。我们对133例涉及8例早期胃癌的137个病变应用了条形活检，其中65.0%仅使用条形活检技术就完全切除。其他病例接受了手术治疗或额外的内镜治疗。16例经胃手术证实已完全切除。另外71例因身体状况不适合手术的患者接受了2至48个月的内镜随访，未出现任何复发情况。基于这项研究，我们认为早期胃癌的条形活检治疗除手术治疗外也应得到评估，特别是对于仅局限于黏膜的小病变病例。
