[Evaluation of BRM in skin cancer].

Biological response modifiers (BRMs) strengthen the host defense mechanism/subsequently producing therapeutic effects against neoplastic and other diseases. Many kinds of BRM are applied for malignant skin tumors. Administration is both systemic and intratumoral, evaluable lesions can be measured in one, two and three directions. Furthermore there are also methods for judging the effects by clinical symptoms. These involve evaluation of macroscopic effect, from which it is possible histopathological judgement. Therefore, the evaluation of effects on skin cancer is very complex, and a new method is necessary. Accordingly we devised a method of judgement summarizing these evaluation procedures.