Krajícková J, Macek J
Research Institute of Rheumatic Diseases, Praha, Czechoslovakia.
Ann Rheum Dis. 1988 Jun;47(6):468-71. doi: 10.1136/ard.47.6.468.
The excretion of sugar components of glycosaminoglycans in the urine was investigated in 19 healthy controls, 27 patients with rheumatoid arthritis, and 24 with osteoarthritis. Both groups of patients excreted significantly more glucosamine, galactosamine, and mannose than the controls. The total uronic acid excretion, also, was higher in the two groups than in the healthy subjects. The possibility of using this method for the long term follow up of rheumatoid arthritis and osteoarthritis and the response to treatment is discussed.
对19名健康对照者、27名类风湿性关节炎患者和24名骨关节炎患者的尿液中糖胺聚糖的糖成分排泄情况进行了研究。两组患者的氨基葡萄糖、半乳糖胺和甘露糖排泄量均显著高于对照组。两组的总糖醛酸排泄量也高于健康受试者。讨论了使用该方法对类风湿性关节炎和骨关节炎进行长期随访以及评估治疗反应的可能性。
