Smith F B, Rajdeo H, Panesar N, Bhuta K, Stahl R
Department of Pathology, Westchester County Medical Center, Valhalla, NY.
Arch Pathol Lab Med. 1988 Jul;112(7):742-5.
Fifteen partial parotid salivary gland resection specimens interpreted as benign lymphoepithelial lesion (BLL) were accessioned by our surgical pathology service between January 1983 and December 1986. Twelve of the specimens were removed from 11 prison inmates referred to our hospital, a patient subgroup constituting the source of only 2% of surgical pathology specimens in general. All prison inmates with BLL had a history of intravenous drug use, had developed unexplained lymphadenopathy concurrently with the parotid gland enlargement, and had suspected human immunodeficiency virus (HIV) infection (serologically confirmed in two). Histopathologic features of the parotid gland specimens included atypical follicular hyperplasia and follicular involution, resembling lymph node changes of HIV infection. The clinical and pathologic findings in these cases suggest an association between HIV infection and BLL, and support a previously proposed mechanism for the development of BLL through progressive enlargement of intraparotid lymph nodes.
1983年1月至1986年12月期间，我们外科病理科接收了15份被诊断为良性淋巴上皮病变（BLL）的腮腺部分切除标本。其中12份标本取自转至我院的11名监狱囚犯，该患者亚组仅占外科病理标本总数的2%。所有患有BLL的监狱囚犯都有静脉吸毒史，在腮腺肿大的同时出现了不明原因的淋巴结病，并且怀疑感染了人类免疫缺陷病毒（HIV）（其中2例血清学确诊）。腮腺标本的组织病理学特征包括非典型滤泡增生和滤泡退化，类似于HIV感染的淋巴结变化。这些病例的临床和病理结果提示HIV感染与BLL之间存在关联，并支持先前提出的通过腮腺内淋巴结逐渐肿大而发展为BLL的机制。
