Finfer M D, Gallo L, Perchick A, Schinella R A, Burstein D E
Department of Pathology, New York University Medical Center, New York 10016.
Acta Cytol. 1990 Nov-Dec;34(6):821-6.
Cystic benign lymphoepithelial lesion (BLL), a previously rare lesion of the parotid gland consisting of marked lymphoid hyperplasia with accompanying squamous-lined cysts, has recently been described in patients with the acquired immune deficiency syndrome (AIDS) or AIDS risk factors. Thirteen fine needle aspiration (FNA) samples of parotid gland masses from patients with AIDS (one case), AIDS risk factors (five cases) or denial of AIDS risk factors (two cases) and a histopathologic diagnosis of BLL were examined. The FNA features that correlated best with the histopathologic findings were (1) a heterogeneous lymphoid population, (2) scattered single and/or clustered foamy macrophages and (3) superficial and/or anucleated squamous cells. Most aspirates showed some combination of these three components. The differential diagnostic considerations, the clinical and radiologic correlations and the relationship of this lesion to HIV infection are discussed. Patients with parotid masses whose aspirates consist of some combination of squamous cells, lymphocytes and foamy macrophages should be questioned for possible AIDS risk factors.
囊性良性淋巴上皮病变（BLL），一种以前在腮腺中罕见的病变，由显著的淋巴样增生及伴随的鳞状内衬囊肿组成，最近在获得性免疫缺陷综合征（AIDS）患者或有AIDS危险因素的患者中被描述。对13例来自AIDS患者（1例）、有AIDS危险因素的患者（5例）或否认有AIDS危险因素的患者（2例）且经组织病理学诊断为BLL的腮腺肿块细针穿刺（FNA）样本进行了检查。与组织病理学结果最相关的FNA特征为：（1）淋巴细胞群体异质性；（2）散在的单个和/或聚集的泡沫状巨噬细胞；（3）表层和/或无核鳞状细胞。大多数抽吸物显示出这三种成分的某种组合。讨论了鉴别诊断的考虑因素、临床和放射学相关性以及该病变与HIV感染的关系。对于腮腺肿块抽吸物由鳞状细胞、淋巴细胞和泡沫状巨噬细胞的某种组合组成的患者，应询问其是否存在可能的AIDS危险因素。
