Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ocul Immunol Inflamm. 2022 May 19;30(4):966-972. doi: 10.1080/09273948.2020.1867871. Epub 2021 Apr 7.
To present the success rate of nonsurgical management of full-thickness inflammatory macular hole (IMH).
Retrospective case series of five patients with IMH.
Five eyes from five patients with IMH enrolled in the current case series. All five eyes had successful closure with corticosteroid in the form of topical, periocular, or intravitreal injections. Systemic immunomodulatory treatment was employed for two patients, in addition to local therapy. For local therapy, one patient received topical eye drops, subtenon injection of corticosteroid, and intravitreal injection of combination of corticosteroid and anti-VEGF was performed in two patients. The closed macular hole reopened in one patient after two years, which required pars plana vitrectomy and anatomical and visual success achieved.
Inflammatory macular holes can be closed with non-surgical interventions, although reopening may occur which requires surgery.
介绍全层炎症性黄斑裂孔（IMH）非手术治疗的成功率。
回顾性病例系列研究，纳入 5 例 IMH 患者。
当前病例系列研究纳入了 5 例 IMH 患者的 5 只眼。所有 5 只眼均通过局部、眼周或玻璃体内注射皮质类固醇成功闭合。除局部治疗外，2 例患者还接受了全身免疫调节治疗。局部治疗中，1 例患者接受了局部滴眼剂治疗，2 例患者接受了皮质类固醇和抗 VEGF 联合的眼周注射和玻璃体内注射。1 例患者在两年后，闭合的黄斑裂孔再次打开，需要进行标准的玻璃体切割手术，最终获得解剖学和视力上的成功。
尽管炎症性黄斑裂孔可以通过非手术干预闭合，但可能会再次打开，需要手术治疗。
