在一只患有糖尿病性黄斑水肿的眼睛中，单次玻璃体内注射阿柏西普后全层黄斑裂孔闭合
Full-Thickness Macular Hole Closure Following a Single Intravitreal Injection of Aflibercept in an Eye With Diabetic Macular Edema.
作者信息
Sharpless Michael, Hogden Michael
机构信息
Department of Ophthalmology, Princess Alexandra Hospital, Woolloongabba, QLD, Australia.
出版信息
J Vitreoretin Dis. 2022 May 5;6(6):457-460. doi: 10.1177/24741264221083415. eCollection 2022 Nov-Dec.
PURPOSE
This work aims to discuss the case of a 32-year-old man with diabetic macular edema (DME) who underwent successful treatment of a full-thickness macular hole (FTMH) with a single dose of aflibercept.
METHODS
A case report is presented.
RESULTS
A 32-year-old man with reduced vision and DME in the right eye was found to have a FTMH. The patient was scheduled for pars plana vitrectomy; however, following a single dose of intravitreal aflibercept, the FTMH closed and the patient avoided surgical intervention.
CONCLUSIONS
FTMH formation in DME is a rare complication that typically requires surgical intervention. We present a case of FTMH closure after a single dose of intravitreal aflibercept, which to our knowledge is the first of its kind. This report highlights the importance of considering conservative treatment initially to avoid surgery.
目的
本研究旨在探讨一名32岁患有糖尿病性黄斑水肿（DME）的男性患者，其单剂量阿柏西普成功治疗了全层黄斑裂孔（FTMH）的病例。
方法
呈现一例病例报告。
结果
一名32岁右眼视力下降且患有DME的男性被发现有FTMH。该患者原计划行玻璃体切除术；然而，在单剂量玻璃体内注射阿柏西普后，FTMH闭合，患者避免了手术干预。
结论
DME中FTMH的形成是一种罕见的并发症，通常需要手术干预。我们报告了一例单剂量玻璃体内注射阿柏西普后FTMH闭合的病例，据我们所知，这是首例此类病例。本报告强调了最初考虑保守治疗以避免手术的重要性。
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