Na Min Chull, Kim Moon Doo, Park Joon Hyuk, Jung Young-Eun, Moon Duk-Soo, Yang Hyun-Ju, Kim Bung-Nyun, Kang Na Ri
Department of Psychiatry, Jeju National University Hospital, Jeju, Korea.
Department of Psychiatry, Jeju National University School of Medicine, Jeju, Korea.
Soa Chongsonyon Chongsin Uihak. 2021 Apr 1;32(2):63-70. doi: 10.5765/jkacap.200045.
Adverse childhood experiences (ACEs) of mothers may negatively affect the mental health of their offspring. Little is known about the intergenerational effect of maternal ACE on post-traumatic stress disorder (PTSD) in the offspring. This study inves-tigated the impact of maternal ACEs on PTSD in the offspring.
A total of 156 mothers with children aged 13-18 years completed the Diagnostic Interview Schedule for Children (DISC) Predictive Scales to determine the presence of psychiatric disorders in their offspring. The subjects completed the ACE questionnaire and the Early Trauma Inventory Self-Report-Short Form. Multivariable logistic regression was used to analyze the relationship between ma-ternal ACEs and PTSD in the offspring.
Of the mothers, 23.7% had at least one ACE, and PTSD was reported in 21.8% of the offspring. The offspring of the mothers in the ACE group had a significantly higher rates of traumatic experiences and PTSD than the offspring of the mothers in the no ACE group. Maternal household dysfunction independently predicted offspring PTSD [odds ratio (OR)=3.008, p=0.05), and three or more maternal ACEs were significantly related to PTSD in the offspring (OR=10.613, p=0.025).
Maternal ACEs have a significant impact on the risk of traumatic experiences and PTSD in the offspring. These findings suggest the presence of intergenerational transmissions by which maternal ACEs affect the mental health of the offspring.
母亲童年期不良经历（ACEs）可能会对其后代的心理健康产生负面影响。关于母亲ACEs对后代创伤后应激障碍（PTSD）的代际影响知之甚少。本研究调查了母亲ACEs对后代PTSD的影响。
共有156名有13 - 18岁孩子的母亲完成了儿童诊断访谈量表（DISC）预测量表，以确定其后代是否存在精神障碍。研究对象完成了ACE问卷和早期创伤量表自我报告简表。采用多变量逻辑回归分析母亲ACEs与后代PTSD之间的关系。
23.7%的母亲至少有一次ACE经历，21.8%的后代报告有PTSD。ACE组母亲的后代经历创伤和患PTSD的比例显著高于无ACE组母亲的后代。母亲家庭功能障碍独立预测后代PTSD（优势比[OR]=3.008，p = 0.05），母亲有三次或更多ACEs与后代PTSD显著相关（OR = 10.613，p = 0.025）。
母亲ACEs对后代经历创伤和患PTSD的风险有显著影响。这些发现表明存在代际传递，即母亲ACEs会影响后代的心理健康。
