Castillo-Aguilar Lizbeth, Ríos-Ponce Alma E, Albano de Mendonca Edson, Villafuerte Gabriel
Clínica Coyoacán, Mexico City, Mexico.
Hospital Psiquiátrico "Dr. Samuel Ramírez Moreno", State of Mexico, Mexico.
Case Rep Psychiatry. 2021 Mar 19;2021:5563017. doi: 10.1155/2021/5563017. eCollection 2021.
Current transcranial magnetic stimulation devices apply intense (near 1 tesla) repetitive magnetic pulses over a specific area of the skull at relatively lower frequencies (1-50 Hz). Nevertheless, different studies have shown that very small magnetic fields, at higher frequencies (50-1000 Hz.), produce therapeutic effects in major depressive disorder. We report the application of high-frequency and low-intensity patterned magnetic pulses over the left prefrontal dorsolateral cortex in three subjects diagnosed with clinical major depressive disorder. All three patients showed sharp changes in their self-reports as well as in the standardized clinical assessment. Hypothesized mechanisms of action of this new variant of magnetic stimulation are discussed.
当前的经颅磁刺激设备以相对较低的频率（1-50赫兹）在颅骨的特定区域施加强烈（接近1特斯拉）的重复磁脉冲。然而，不同的研究表明，非常小的磁场，在较高频率（50-1000赫兹）下，对重度抑郁症有治疗效果。我们报告了在三名被诊断为临床重度抑郁症的受试者的左前额叶背外侧皮质上应用高频和低强度的模式化磁脉冲。所有三名患者在自我报告以及标准化临床评估中都显示出明显变化。本文还讨论了这种新型磁刺激作用机制的假设。
