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Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes.非奈利酮对 2 型糖尿病患者慢性肾脏病结局的影响。
N Engl J Med. 2020 Dec 3;383(23):2219-2229. doi: 10.1056/NEJMoa2025845. Epub 2020 Oct 23.
2
Effects of Canagliflozin in Patients with Baseline eGFR <30 ml/min per 1.73 m: Subgroup Analysis of the Randomized CREDENCE Trial.基线 eGFR<30 ml/min/1.73 m2 的患者中卡格列净的疗效:随机 CREDENCE 试验的亚组分析。
Clin J Am Soc Nephrol. 2020 Dec 7;15(12):1705-1714. doi: 10.2215/CJN.10140620. Epub 2020 Nov 19.
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KDIGO 2020 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease.KDIGO 2020慢性肾脏病糖尿病管理临床实践指南
Kidney Int. 2020 Oct;98(4S):S1-S115. doi: 10.1016/j.kint.2020.06.019.
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Dapagliflozin in Patients with Chronic Kidney Disease.达格列净治疗慢性肾脏病患者。
N Engl J Med. 2020 Oct 8;383(15):1436-1446. doi: 10.1056/NEJMoa2024816. Epub 2020 Sep 24.
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Cardiovascular Outcomes with Ertugliflozin in Type 2 Diabetes.在 2 型糖尿病患者中使用依格列净的心血管结局。
N Engl J Med. 2020 Oct 8;383(15):1425-1435. doi: 10.1056/NEJMoa2004967. Epub 2020 Sep 23.
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Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure.恩格列净治疗心力衰竭的心血管和肾脏结局。
N Engl J Med. 2020 Oct 8;383(15):1413-1424. doi: 10.1056/NEJMoa2022190. Epub 2020 Aug 28.
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Renal Effects of Sulodexide in Type 2 Diabetic Patients without Nephrotic Range Proteinuria.磺达肝癸钠对 2 型糖尿病非肾病范围蛋白尿患者的肾脏作用。
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Diabetes Ther. 2020 Sep;11(9):1983-1999. doi: 10.1007/s13300-020-00888-w. Epub 2020 Aug 5.
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Conversion of Urine Protein-Creatinine Ratio or Urine Dipstick Protein to Urine Albumin-Creatinine Ratio for Use in Chronic Kidney Disease Screening and Prognosis : An Individual Participant-Based Meta-analysis.将尿蛋白肌酐比或尿试纸条蛋白转化为尿白蛋白肌酐比用于慢性肾脏病筛查和预后的研究:一项基于个体参与者的荟萃分析。
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Bardoxolone methyl: drug development for diabetic kidney disease.巴多索隆甲基:用于治疗糖尿病肾病的药物研发。
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糖尿病患者的慢性肾脏病

Chronic kidney disease in patients with diabetes mellitus.

作者信息

Nordheim Espen, Geir Jenssen Trond

机构信息

Department of Transplantation Medicine, Section of Nephrology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.

Faculty of Medicine, University of Oslo, Oslo, Norway.

出版信息

Endocr Connect. 2021 Apr 29;10(5):R151-R159. doi: 10.1530/EC-21-0097.

DOI:10.1530/EC-21-0097
PMID:33830068
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8111312/
Abstract

Chronic kidney disease is a common complication and concomitant condition of diabetes mellitus. The treatment of patients with diabetes and chronic kidney disease, including intensive control of blood sugar and blood pressure, has been very similar for type 1 and type 2 diabetes patients. New therapeutic targets have shown promising results and may lead to more specific treatment options for patients with type 1 and type 2 diabetes.

摘要

慢性肾脏病是糖尿病常见的并发症和并存疾病。1型和2型糖尿病患者中,糖尿病合并慢性肾脏病患者的治疗,包括强化血糖和血压控制,一直非常相似。新的治疗靶点已显示出有前景的结果,可能会为1型和2型糖尿病患者带来更具针对性的治疗选择。