Dr Shiblee Sadeque Shakil, Senior Consultant, Department of Cardiology, Mymensingh Medical College Hospital, Mymensingh, Bangladesh; E-mail:
Mymensingh Med J. 2021 Apr;30(2):281-291.
Rheumatic heart disease causes a substantial number of morbidity and mortality in South Asia. With the increasing urbanization & antibiotic availability, it is now in declining trends. The prevalence of Rheumatic Fever and Chronic Rheumatic Heart Disease in Bangladesh is 0.6 and 0.3 per thousand populations, respectively. Mitral valve is mostly involved in the rheumatic process, particularly in the form of mitral stenosis. Treatment options of mitral stenosis depend upon the severity of the disease. Echocardiography has a key role in determining the pattern, extent and severity of the involvement of the mitral valve apparatus. 2D and Doppler echocardiography are conventionally used. 3D echocardiography is more available nowadays. The heart being a complex three-dimensional structure, a 3D evaluation would definitely offer better visualization for accurate assessment of the severity of rheumatic mitral stenosis. There are many echocardiography based scoring systems are available for the assessment of the severity of rheumatic MS. Those are mostly 2DE based; among them, Wilkins is widely practiced. Real-time 3DE based score for mitral stenosis is developed recently. This cross-sectional observational study was done in the University Cardiac Centre, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from May 2012 to October 2012. Considering all ethical issues, data were collected from 50 subjects who underwent transthoracic 2D and 3D Echocardiography for the assessment of the extent and severity of mitral stenosis. Precise measurement of the mitral valvular area is of a pivotal role in the assessment of severity, which is found almost similar by both 2DE (0.98±0.24cm²) and 3DE (0.92±0.23cm²). But in identifying calcification and its extent specifically commissural involvement is better detected by 3DE (p=0.002). Detail assessment of subvalvular involvement particularly chordal adhesion can better be done by 3DE (p<0.001). All of these have important contributions in formulating the most favorable therapeutic roadmap in chronic rheumatic MS. To make an efficient management plan and also for the confident prediction of complications, three-dimensional echocardiography has promising prospects and should be considered as an important adjuvant to the conventional two-dimensional echocardiography.
风湿性心脏病在南亚导致了大量的发病率和死亡率。随着城市化和抗生素的普及,风湿性心脏病的发病率正在下降。孟加拉国风湿热和慢性风湿性心脏病的患病率分别为每千人 0.6 和 0.3。风湿性过程主要累及二尖瓣,特别是二尖瓣狭窄的形式。二尖瓣狭窄的治疗选择取决于疾病的严重程度。超声心动图在确定二尖瓣装置受累的模式、程度和严重程度方面起着关键作用。二维和多普勒超声心动图通常用于临床。如今,三维超声心动图更为普及。心脏是一个复杂的三维结构,三维评估肯定会提供更好的可视化效果,从而更准确地评估风湿性二尖瓣狭窄的严重程度。有许多基于超声心动图的评分系统可用于评估风湿性 MS 的严重程度。这些评分系统大多基于二维超声心动图,其中,Wilkins 评分系统应用最为广泛。最近开发了一种基于实时三维超声心动图的二尖瓣狭窄评分系统。本研究为横断面观察性研究,于 2012 年 5 月至 2012 年 10 月在孟加拉国达卡的 Bangabandhu Sheikh Mujib 医科大学(BSMMU)大学心脏中心进行。考虑到所有伦理问题,从 50 名接受经胸二维和三维超声心动图评估二尖瓣狭窄程度和范围的患者中收集数据。准确测量二尖瓣瓣口面积在评估严重程度方面起着至关重要的作用,二维超声心动图(0.98±0.24cm²)和三维超声心动图(0.92±0.23cm²)的测量结果几乎相同。但是,在识别钙化及其程度方面,特别是在识别瓣交界累及方面,三维超声心动图的检测效果更好(p=0.002)。在评估瓣下结构,特别是腱索粘连方面,三维超声心动图的评估效果更好(p<0.001)。所有这些都为制定慢性风湿性 MS 最有利的治疗方案提供了重要依据。为了制定有效的管理计划,并对并发症做出有信心的预测,三维超声心动图具有广阔的前景,应被视为二维超声心动图的重要辅助手段。