Dr Nureza Islam, Lecturer, Department of Anatomy, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:
Mymensingh Med J. 2021 Apr;30(2):337-342.
This cross-sectional analytical study was conducted in the department of Paediatrics, Mymensingh Medical College Hospital (MMCH), Mymensingh, Bangladesh from March 2017 to August 2018 to assess the pattern of serum iron profile and red cell indices in children with severe acute malnutrition. Seventy children having severe acute malnutrition were compared with 70 age matched children those had normal growth. Age range of the studied children was 6 months to 59 completed months. Male was found predominant (54.3%) in both study group and comparison group. Mean serum iron, serum ferritin, serum total iron binding capacity and transferrin saturation in severely malnourished children were 45.3±19.3μg/dl, 26.5±20.0ng/ml, 246.3±47.5μg/dl and 16.4±2.0% respectively which were significantly lower than that of healthy children (p<0.05). Mean Hb level in children with severe acute malnutrition was found 8.3±1.6gm/dl which was also found significantly lower than that of normal children (p<0.05). Anaemia was found in all (100%) severely malnourished children compared to 25.7% of children in comparison group. Mean MCV, MCH and MCHC in children with severe acute malnutrition was found 71.7±13.5fl, 24.0±5.8pg and 31.4±4.0gm/dl respectively which were significantly lower than that of comparison group (p<0.05). Serum iron profile and red cell indices should be routinely done in severely malnourished children for early intervention and management of iron deficiency anaemia.
本横断面分析性研究于 2017 年 3 月至 2018 年 8 月在孟加拉国迈门辛医科大学医院儿科进行，旨在评估严重急性营养不良儿童的血清铁谱和红细胞指数模式。将 70 名患有严重急性营养不良的儿童与 70 名具有正常生长的年龄匹配儿童进行比较。研究儿童的年龄范围为 6 个月至 59 个完整月。在研究组和对照组中，男性均占优势（54.3%）。严重营养不良儿童的平均血清铁、血清铁蛋白、血清总铁结合力和转铁蛋白饱和度分别为 45.3±19.3μg/dl、26.5±20.0ng/ml、246.3±47.5μg/dl 和 16.4±2.0%，明显低于健康儿童（p<0.05）。严重急性营养不良儿童的平均 Hb 水平为 8.3±1.6gm/dl，也明显低于正常儿童（p<0.05）。与对照组的 25.7%相比，所有（100%）严重营养不良儿童均存在贫血。严重急性营养不良儿童的平均 MCV、MCH 和 MCHC 分别为 71.7±13.5fl、24.0±5.8pg 和 31.4±4.0gm/dl，明显低于对照组（p<0.05）。严重营养不良儿童应常规进行血清铁谱和红细胞指数检查，以便及早进行铁缺乏性贫血的干预和管理。
