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孟加拉国缺铁性贫血青少年女性血清铁蛋白水平现状。

Status of Serum Ferritin Level among Iron Deficiency Anemic Adolescent Girls in Bangladesh.

机构信息

Dr Lily Afroz, Lecturer, Department of physiology, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:

出版信息

Mymensingh Med J. 2022 Oct;31(4):891-893.

PMID:36189528
Abstract

Adolescence explained as a period of age between 10 to 19 years. This is a major contributing period to build up the health of girls. Ferritin is an intracellular protein that contains iron and releases it in a controlled fashion and it reflects body iron stores and systemic inflammation during adolescent period. It is considered the best single test for the diagnosis of iron deficiency anemia during adolescent because its concentration is directly proportional to total body iron stores in adolescent period. This study was done in the Department of Physiology, Mymensingh Medical College, Mymensingh, Bangladesh to evaluate the changes of serum ferritin levels among iron deficient anemic adolescent girls in comparison to healthy adolescent girls in Bangladesh. This was a cross sectional, prospective, analytical type of study. This study ranged from 10-19 years of adolescent girls. Seventy (70) healthy adolescent girls, as control group (Group I). Seventy (70) iron deficiency anemic adolescent girls as study group (Group II). Serum ferritin was estimated by Micro-particle Enzyme Immunoassay Test Kit. Data were expressed as mean (±SD). Statistical significance of difference among the Group I and Group II were calculated by unpaired students 't' test. The mean±SD level of serum ferritin among Group I and Group II were 26.22±4.03μg/L and 13.33±3.18μg/L respectively. Mean values ±SD of serum ferritin significantly lower in (Group II) in comparison with (Group I). Higher numbers of adolescent girls are still suffering from anemia along with low level of serum ferritin in Bangladesh. For combat this situation, immediate, sustainable and long term public health intervention and nutritional supplementation must be required.

摘要

青春期解释为 10 至 19 岁之间的年龄段。这是一个主要的贡献时期,以建立女孩的健康。铁蛋白是一种细胞内蛋白质,它含有铁,并以受控的方式释放它,它反映了青春期的身体铁储存和全身炎症。它被认为是诊断青春期缺铁性贫血的最佳单项检查,因为其浓度与青春期的总身体铁储存成正比。这项研究是在孟加拉国迈门辛医学院生理学系进行的,目的是评估血清铁蛋白水平在缺铁性贫血的青春期少女与健康青春期少女之间的变化。这是一项横断面、前瞻性、分析性研究。这项研究的年龄范围为 10-19 岁的青春期少女。70 名健康的青春期少女作为对照组(I 组)。70 名缺铁性贫血的青春期少女作为研究组(II 组)。血清铁蛋白用微粒酶免疫测定试剂盒测定。数据表示为均值(±SD)。用未配对学生 t 检验计算 I 组和 II 组之间的差异的统计学意义。I 组和 II 组的血清铁蛋白均值±SD 分别为 26.22±4.03μg/L 和 13.33±3.18μg/L。与 I 组相比,II 组的血清铁蛋白均值±SD 值明显降低。在孟加拉国,仍有大量青春期少女患有贫血和低血清铁蛋白。为了应对这种情况,必须立即采取可持续和长期的公共卫生干预和营养补充措施。

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