Nanchang Hongdu Hospital of Traditional Chinese Medicine.
Jiangxi University of Traditional Chinese Medicine, Nanchang, PR China.
Medicine (Baltimore). 2021 Apr 9;100(14):e25393. doi: 10.1097/MD.0000000000025393.
The aim of this study is to provide the methods used to evaluate the effectiveness and safety of acupuncture therapy for treating drooling in children with cerebral palsy.
A comprehensive search of Pubmed, Embase, Cochrane Central Register of Controlled Trials, Web of Science, 4 Chinese databases (China National Knowledge Infrastructure, Chinese Biomedical Literatures database, Wan-Fang Database and Chinese Science and Technology Periodicals will be conducted to identify randomized controlled trials of acupuncture for treating children with cerebral palsy salivation with no restriction on time or language. The primary outcome of this systematic review will be the effective rate. The risk of bias will be implemented according to Cochrane Handbook for Systematic Reviews of Interventions. We will conduct the meta-analysis to synthesize the evidence for each outcome, if possible. The heterogeneity will be evaluated statistically using the χ2 test and the I2 statistic. The random-effect model will be used to provide more conservative results, if significant heterogeneity is identified (I2 > 50% or P < .10).
ETHICS/DISSEMINATION: Our findings will be disseminated in a peer-reviewed journal and at conference meetings. It is not necessary for formal ethical approval as no primary data are collected.
INPLASY2020110024.
本研究旨在提供评估针刺疗法治疗脑瘫儿童流涎疗效和安全性的方法。
我们将全面检索 Pubmed、Embase、Cochrane 中央对照试验注册库、Web of Science、4 个中文数据库（中国知网、中国生物医学文献数据库、万方数据库和中国科技期刊数据库），以确定时间或语言不受限制的针刺治疗脑瘫儿童流涎的随机对照试验。本系统评价的主要结局指标为有效率。将根据 Cochrane 干预系统评价手册实施偏倚风险评估。如果可能，我们将对每个结局进行荟萃分析以综合证据。如果存在显著异质性（I2>50%或 P<.10），将使用 χ2 检验和 I2 统计量进行统计学评估。如果存在显著异质性，将使用随机效应模型提供更保守的结果。
伦理/传播：我们的研究结果将发表在同行评议的期刊和会议上。由于未收集原始数据，因此不需要正式的伦理批准。
INPLASY2020110024。
