Dirección Médica, Hospital Clínico Universitario, Valladolid, España.
Servicio de Cardiología, Hospital Clínico Universitario, Valladolid, España.
Med Clin (Barc). 2021 Jul 9;157(1):22-32. doi: 10.1016/j.medcli.2021.01.017. Epub 2021 Apr 5.
Influenza infection has been identified as a triggering or exacerbating factor for cardiovascular events. To analyse the effect of influenza vaccination on cardiovascular disease, a systematic search of studies published between 2009-2019 was conducted. All the studies that evaluated the effect of vaccination against influenza on cardiovascular events and their outcome were considered. Finally, 30 of the 1147 identified studies were included. These studies show a protective effect of the influenza vaccine on the development of cardiovascular events (myocardial infarction, cerebrovascular accidents, atrial fibrillation, and heart failure) and on the worsening of these conditions. Furthermore, the data showed that vaccinated patients have a lower risk of death from cardiovascular pathologies. Influenza vaccination is therefore an effective measure in the prevention of cardiovascular diseases both in patients with established cardiovascular disease and in the population without previous coronary pathology.
流感感染已被确定为心血管事件的触发或加重因素。为了分析流感疫苗接种对心血管疾病的影响，对 2009 年至 2019 年间发表的研究进行了系统检索。考虑了所有评估流感疫苗接种对心血管事件及其结局影响的研究。最后，从 1147 项已确定的研究中纳入了 30 项研究。这些研究表明流感疫苗对心血管事件（心肌梗死、脑血管意外、心房颤动和心力衰竭）的发展及其恶化具有保护作用。此外，数据显示，接种疫苗的患者死于心血管疾病的风险较低。因此，流感疫苗接种是预防既有心血管疾病患者和无先前冠状动脉疾病人群心血管疾病的有效措施。
