大网膜作为胰岛移植的部位。
The greater omentum as a site for pancreatic islet transplantation.
作者信息
Pellicciaro M, Vella I, Lanzoni G, Tisone G, Ricordi C
机构信息
Liver Transplant Center, Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy.
Diabetes Research Institute and Cell Transplant Center, University of Miami, Miami, FL, USA.
出版信息
CellR4 Repair Replace Regen Reprogram. 2017;5(3). Epub 2017 Jun 20.
Abstract
The greater omentum is a highly vascularized anatomical structure in the peritoneal cavity. Its main components are connective, adipose and vascular cells, along with specialized immune cells. The omentum functions as a site for fat accumulation, it has adhesive properties to control traumatized and inflamed tissues, and a function in local hemostasis, immune responses, and revascularization. Other functions include the absorption of fluids, the phagocytosis of particulate matter, and foreign body reaction. The omentum is catalyzing significant interest for its potential as a site for pancreatic islet and cell transplantation. Our knowledge about this structure, its functions, and its potential as a site for transplantation is poised to grow in the coming years.
摘要
大网膜是腹腔内一个血管高度丰富的解剖结构。其主要成分是结缔组织细胞、脂肪细胞和血管细胞，以及特殊的免疫细胞。大网膜作为脂肪堆积的场所，具有黏附特性以控制受创伤和发炎的组织，并在局部止血、免疫反应和血管再生中发挥作用。其他功能包括液体吸收、颗粒物吞噬作用和异物反应。大网膜因其作为胰岛和细胞移植部位的潜力而引发了极大的关注。我们对这一结构、其功能以及作为移植部位的潜力的认识在未来几年有望不断增长。
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