Hess D, Ohishi H, Skinner M, Cohen A S, Schmid K
Department of Biochemistry, Boston University School of Medicine, MA 02118.
Clin Chim Acta. 1988 Apr 29;173(3):331-5. doi: 10.1016/0009-8981(88)90022-8.
The carbohydrate moiety of human serum amyloid P component was analyzed and found to consist of equal amounts of galactose and mannose (total 4.0%), of glucosamine and galactosamine in a ratio of 7:1 (total 2.7%) and sialic acid (3.9%). It should be noted that this is the first report on the separate quantification of the neutral hexoses and the demonstration of the presence of galactosamine. The contents of glucosamine and galactosamine suggest that this protein possesses both an N- and an O-glycan.
对人血清淀粉样蛋白P成分的碳水化合物部分进行了分析，发现其由等量的半乳糖和甘露糖（总计4.0%）、比例为7:1的葡萄糖胺和半乳糖胺（总计2.7%）以及唾液酸（3.9%）组成。应当指出，这是关于中性己糖单独定量以及半乳糖胺存在证明的首份报告。葡萄糖胺和半乳糖胺的含量表明该蛋白质同时具有N - 聚糖和O - 聚糖。
