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移植患者无痛性皮疹。

Painless rash in a transplant patient.

机构信息

Dermatology Department, Centro Hospitalar Universitário do Porto, Porto, Portugal.

Pathology Department, Centro Hospitalar Universitário do Porto, Porto, Portugal.

出版信息

Transpl Infect Dis. 2021 Aug;23(4):e13613. doi: 10.1111/tid.13613. Epub 2021 Apr 27.

DOI:10.1111/tid.13613
PMID:33835649
Abstract

Dermatophytes are common keratinophilic fungi responsible for superficial skin infections. Deep dermatophytosis is a rare form of invasive skin infection described in immunocompromised patients. We report the case of a 65-year-old man with a history of an orthotopic liver transplant for hepatocarcinoma 6 months earlier, who presented with small painless erythematous papules in lower limbs, some of which were umbilicated. Skin biopsy showed an intense non-necrotizing granulomatous reaction in the dermis around fungal structures. Trichophyton rubrum was identified as the causal agent through culture and internal transcribed spacer sequencing.

摘要

皮肤癣菌是常见的亲角质真菌,可引起皮肤浅表感染。深部皮肤癣菌病是一种罕见的侵袭性皮肤感染形式,见于免疫功能低下的患者。我们报告了 1 例 65 岁男性病例,6 个月前因肝癌行原位肝移植,他下肢出现小而无痛的红斑丘疹,部分呈脐状。皮肤活检显示真皮内围绕真菌结构存在强烈的非坏死性肉芽肿反应。通过培养和内部转录间隔区测序鉴定出红色毛癣菌为致病因子。

相似文献

1
Painless rash in a transplant patient.移植患者无痛性皮疹。
Transpl Infect Dis. 2021 Aug;23(4):e13613. doi: 10.1111/tid.13613. Epub 2021 Apr 27.
2
Deep-seated dermatophytosis caused by Trichophyton rubrum in patient with Becker muscular dystrophy.贝克肌肉营养不良患者由红色毛癣菌引起的深部皮肤癣菌病
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Erythroderma combined with deeper dermal dermatophytosis due to Trichophyton rubrum in a patient with myasthenia gravis: first case report and literature review.红皮病合并深部皮肤癣菌病(由红色毛癣菌引起):重症肌无力患者的首例病例报告及文献复习。
BMC Infect Dis. 2023 Nov 13;23(1):789. doi: 10.1186/s12879-023-08752-5.
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Simultaneous dermatophytosis and keratomycosis caused by Trichophyton interdigitale infection: a case report and literature review.由须癣毛癣菌感染引起的同时性皮肤癣菌病和真菌性角膜炎:一例病例报告及文献复习。
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Deep dermatophytosis caused by Trichophyton rubrum in immunocompromised patients.免疫功能低下患者感染红色毛癣菌引起的深部皮肤癣菌病。
An Bras Dermatol. 2022 Mar-Apr;97(2):223-227. doi: 10.1016/j.abd.2021.05.014. Epub 2022 Jan 20.
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Multiple abscesses in the lower extremities caused by Trichophyton rubrum.下肢多处红色毛癣菌引起的脓肿。
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Extensive deep dermatophytosis cause by Trichophyton rubrum in a patient with liver cirrhosis and chronic renal failure.广泛深部皮肤癣菌病由红色毛癣菌引起,患者患有肝硬化和慢性肾衰竭。
Mycopathologia. 2013 Dec;176(5-6):457-62. doi: 10.1007/s11046-013-9696-2. Epub 2013 Aug 28.
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Deep dermatophytosis caused by Trichophyton rubrum in an elderly patient with CARD9 deficiency: A case report and literature review.老年 CARD9 缺陷患者红色毛癣菌引起的深部皮肤癣菌病:病例报告及文献复习。
J Dermatol. 2024 Feb;51(2):294-300. doi: 10.1111/1346-8138.16995. Epub 2023 Oct 7.
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Trichophyton onychomycosis and deep dermatophytosis in a post-heart transplant patient.心脏移植术后患者的须癣毛癣菌甲真菌病和深部皮肤癣菌病。
Transpl Infect Dis. 2022 Jun;24(3):e13830. doi: 10.1111/tid.13830. Epub 2022 Apr 6.
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A 61-year-old man with erythematous forearm papules three months after liver transplantation.一名61岁男性在肝移植术后三个月出现前臂红斑丘疹。
Transpl Infect Dis. 2018 Jun;20(3):e12869. doi: 10.1111/tid.12869. Epub 2018 Mar 25.

引用本文的文献

1
Erythroderma combined with deeper dermal dermatophytosis due to Trichophyton rubrum in a patient with myasthenia gravis: first case report and literature review.红皮病合并深部皮肤癣菌病(由红色毛癣菌引起):重症肌无力患者的首例病例报告及文献复习。
BMC Infect Dis. 2023 Nov 13;23(1):789. doi: 10.1186/s12879-023-08752-5.