Department of Sensorimotor Neuroscience, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553 Japan; Department of Physical Therapy, Nagoya University Graduate School of Medicine, Nagoya, Japan.
The Graduate School of Core Ethics and Frontier Sciences, Ritsumeikan University, Kyoto, Japan.
Neuroimage. 2021 Jul 15;235:118022. doi: 10.1016/j.neuroimage.2021.118022. Epub 2021 Apr 6.
Control of movements using visual information is crucial for many daily activities, and such visuomotor control has been revealed to be supported by alpha and beta cortical oscillations. However, it has been remained to be unclear how midfrontal theta and occipital gamma oscillations, which are associated with high-level cognitive functions, would be involved in this process to facilitate performance. Here we addressed this fundamental open question in healthy young adults by measuring high-density cortical activity during a precision force-matching task. We manipulated the amount of error by changing visual feedback gain (low, medium, and high visual gains) and analyzed event-related spectral perturbations. Increasing the visual feedback gain resulted in a decrease in force error and variability. There was an increase in theta synchronization in the midfrontal area and also in beta desynchronization in the sensorimotor and posterior parietal areas with higher visual feedback gains. Gamma de/synchronization was not evident during the task. In addition, we found a moderation effect of midfrontal theta on the positive relationship between the beta oscillations and force error. Subsequent simple slope analysis indicated that the effect of beta oscillations on force error was weaker when midfrontal theta was high. Our findings suggest that the midfrontal area signals the increased need of cognitive control to refine behavior by modulating the visuomotor processing at theta frequencies.
使用视觉信息来控制运动对于许多日常活动至关重要，而这种运动控制已被证明是由皮质α和β振荡支持的。然而，中前额θ和枕部γ振荡如何参与这一过程以促进表现，仍然不清楚。这些振荡与高级认知功能有关。在这里，我们通过测量健康年轻人在精确力匹配任务期间的高密度皮质活动来解决这个基本的开放性问题。我们通过改变视觉反馈增益（低、中、高视觉增益）来操纵误差量，并分析事件相关频谱扰动。增加视觉反馈增益会导致力误差和变异性减小。随着更高的视觉反馈增益，中前额区域的θ同步增加，而感觉运动和后顶叶区域的β去同步增加。在任务期间，γ去/同步不明显。此外，我们发现中前额θ对β振荡与力误差之间的正相关关系具有调节作用。随后的简单斜率分析表明，当中前额θ较高时，β振荡对力误差的影响较弱。我们的研究结果表明，中前额区域通过调制θ频率的运动处理来发出信号，表明需要增加认知控制来改善行为。
