Department of Urology, Austin Health, Melbourne, VIC, Australia.
Division of Urology, Department of Surgery, University of Saskatchewan, Saskatoon, SK, Canada.
World J Urol. 2021 Oct;39(10):3931-3938. doi: 10.1007/s00345-021-03691-9. Epub 2021 Apr 9.
To review the evolution of female continence surgical practice in Australia over the last 20 years and observe whether vaginal mesh controversies impacted these trends.
From January 2000 to December 2019, medicare benefit schedule codes for female continence procedures were identified and extracted for: mesh sling, fascial sling, bulking agent, female urethral prosthesis, colposuspension, and removal of sling. Population-adjusted incidences per 100,000 persons were calculated using publicly available demographic data. Three discrete phases were defined over the study time frame for analysis: 2000-2006; 2006-2017, and 2017-2019. Interrupted time-series analyses were conducted to assess for impact on incidence at 2006 and 2017.
There were 119,832 continence procedures performed in Australia from 2000 to 2019, with the mid-urethral sling (MUS) the most common (72%). The majority of mesh (n = 63,668, 73%) and fascial sling (n = 1864, 70%) procedures were in women aged < 65 years. Rates of mesh-related procedures steeply declined after 2017 (initial change: -21 cases per 100,000; subsequent rate change: -12 per 100,000, p < 0.001). Non-mesh related/bulking agents increased from + 0.34 during 2006-2017 to + 2.1 per 100,000 after 2017 (p < 0.001). No significant change in mesh extraction was observed over 2006-2017 (+ 0.06 per 100,000, p = 0.192). There was a significant increase in mesh extraction procedures after 2017 (0.83 per 100,000, p < 0.001).
Worldwide, controversy surrounding vaginal mesh had a significant impact on Australian continence surgery trends. The most standout trends were observed after the 2017 Australian class-action lawsuit and Senate Inquiry.
回顾过去 20 年澳大利亚女性控尿手术实践的演变,并观察阴道网片争议是否对这些趋势产生了影响。
从 2000 年 1 月至 2019 年 12 月,确定并提取了医疗保险福利计划代码,用于女性控尿程序:网片吊带、筋膜吊带、填充剂、女性尿道假体、耻骨后悬吊术和网片去除术。使用公开的人口统计数据计算每 10 万人的人口调整发病率。在研究时间段内定义了三个离散阶段进行分析:2000-2006 年;2006-2017 年和 2017-2019 年。进行了中断时间序列分析,以评估 2006 年和 2017 年的发病率变化。
2000 年至 2019 年,澳大利亚共进行了 119832 次控尿手术,其中最常见的是中尿道吊带(MUS)(72%)。大多数网片(n=63668,73%)和筋膜吊带(n=1864,70%)手术都在<65 岁的女性中进行。2017 年后,与网片相关的手术率急剧下降(初始变化:每 10 万人减少 21 例;随后的变化率:每 10 万人减少 12 例,p<0.001)。非网片相关/填充剂从 2006-2017 年增加了+0.34 至 2017 年后每 10 万人增加 2.1(p<0.001)。2006-2017 年期间,网片提取无明显变化(每 10 万人增加 0.06,p=0.192)。2017 年后,网片提取手术明显增加(每 10 万人增加 0.83,p<0.001)。
在全球范围内,阴道网片的争议对澳大利亚控尿手术趋势产生了重大影响。在 2017 年澳大利亚集体诉讼和参议院调查之后,观察到了最显著的趋势。