遗传学在心房颤动管理中的作用。
Role of genetics in atrial fibrillation management.
机构信息
Department of Cardiology, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.
Cardiovascular Disease Initiative, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
出版信息
Europace. 2021 Apr 10;23(23 Suppl 2):ii4-ii8. doi: 10.1093/europace/euaa366.
Atrial fibrillation (AF) management has significantly improved during the career of professor Crijns. Research was implemented into guidelines and clinical practice. However, despite advances in AF management, large differences between individual treatment responses still exist and the mechanisms underlying initiation and perpetuation of AF are not completely understood. International collaborations have revealed the genetic contribution to AF and steps towards improving AF management are being made. In this short review, the most important paradigms shifts in the field of AF genetics are recognized and the future role of genetics in personalized management of AF is discussed.
心房颤动（AF）的管理在 Crijns 教授的职业生涯中得到了显著改善。研究被纳入了指南和临床实践。然而，尽管 AF 的管理取得了进展，但个体治疗反应之间仍存在很大差异，AF 的起始和维持机制尚不完全清楚。国际合作揭示了 AF 的遗传贡献，正在朝着改善 AF 管理的方向迈进。在这篇简短的综述中，我们认识到 AF 遗传学领域最重要的范式转变，并讨论了遗传学在 AF 个体化管理中的未来作用。
Zotero 插件