Himes J E, Duff I F
J Int Med Res. 1977;5(6):412-6. doi: 10.1177/030006057300100205.
In 88.9% of a group of 18 patients with rheumatoid arthritis participating in an open-label study with fenoprofen calcium (Nalfon), there was observed a mean titre decrease in level of rheumatoid factor as compared to baseline levels. In follow-up, three months to one year later, a uniform titre increase above the mean level of the study period had occurred. In all cases the titre returned to baseline levels or higher.
在18名参与布洛芬钙（萘普生）开放标签研究的类风湿性关节炎患者中，88.9%的患者类风湿因子水平与基线水平相比出现了平均滴度下降。在后续随访中，三到一年后，滴度普遍升高至高于研究期间的平均水平。在所有病例中，滴度恢复到基线水平或更高。
