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Longterm fenoprofen therapy in patients with rheumatoid arthritis.

作者信息

Roth S H, Englund D W, Harris B K

出版信息

J Rheumatol. 1976;2:43-8.

PMID:781230
Abstract

Fenoprofen, a new antirheumatic agent, was evaluated in 45 patients with rheumatoid arthritis in an open study design to simulate the conditions under which the drug will be used. No control agents were used. The effectiveness of fenoprofen was demonstrated by the per cent of patients who improved during fenoprofen therapy. Duration of therapy varied from one to 629 days. Pain was the first parameter to respond, followed by an anti-inflammatory effect, which was observed after four to six weeks of therapy. Side effects consisted mainly of minor gastro-intestinal symptoms.

摘要

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引用本文的文献

1
Pain management for inflammatory arthritis (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and other spondylarthritis) and gastrointestinal or liver comorbidity.炎症性关节炎(类风湿关节炎、银屑病关节炎、强直性脊柱炎及其他脊柱关节炎)与胃肠道或肝脏合并症的疼痛管理。
Cochrane Database Syst Rev. 2012 Jan 18;1(1):CD008951. doi: 10.1002/14651858.CD008951.pub2.
2
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents.新型非甾体抗炎药对上消化道影响的综述
Dig Dis Sci. 1979 Jan;24(1):53-64. doi: 10.1007/BF01297239.
3
Fenoprofen: a review of its pharmacological properties and therapeutic efficacy in rheumatic diseases.
非诺洛芬:其药理特性及在风湿性疾病中治疗效果的综述
Drugs. 1977 Apr;13(4):241-65. doi: 10.2165/00003495-197713040-00001.