Ding Haoxuan, Zhang Qian, Xu Huangen, Yu Xiaonan, Chen Lingjun, Wang Zhonghang, Feng Jie
College of Animal Sciences, Zhejiang University, Key Laboratory of Animal Feed and Nutrition of Zhejiang Province, Hangzhou, China.
Research Center of Zhejiang Kesheng Feed Co., Ltd., Shaoxing, Zhejiang, China.
Ecotoxicol Environ Saf. 2021 Apr 8;216:112177. doi: 10.1016/j.ecoenv.2021.112177.
Dietary copper and zinc additives facilitate the growth and development of animals, but heavy metal in feces threatens the ecological environment, and balance is the key to solving the problem. In this study, a trial of 2000 pigs (early nursery, 9-15 kg; late nursery, 15-25 kg; grower: 25-60 kg) was conducted to analyze the effects of different diets (gradient dosage of copper and zinc additives) on growth performance, antioxidant performance, immune function, and fecal heavy metal excretion of piglets and growing pigs. Although no significant differences were observed in average daily gain (ADG) and average daily feed intake (ADFI) between treatments during the entire nursery-grower period, the addition of appropriate high doses of copper and zinc to the diet had a beneficial effect on the antioxidant status and immune function of weaned piglets. Especially at early nursery, compared with the low-copper group (5 mg/kg Cu), the high-copper group (120 mg/kg Cu) could significantly increase the peroxidase (POD), glutathione peroxidase (GSH-PX), total antioxidant capacity (T-AOC), catalase (CAT) and copper/zinc superoxide dismutase (Cu/Zn-SOD), cortisol in the serum. Moreover, the addition of zinc and copper in the diet not only increased the concentration of corresponding trace elements in the serum, but also affected the concentration of other trace elements in the serum. The reduction of copper and zinc content in the diet contributed to reducing the copper and zinc content in feces. In conclusion, we have formulated the mutual benefit dosages of copper and zinc (9-15 kg: 5 mg/kg Cu and 50 mg/kg Zn; 15-25 kg: 4 mg/kg Cu and 50 mg/kg Zn; 25-60 kg: 4 mg/kg Cu and 10 mg/kg Zn) for weaning piglets and growing pigs, which would help ensure the healthy growth of animals and reduce environmental heavy metal residues. CAPSULE: This study developed a mutually beneficial dose of copper and zinc in pig diets, which promotes animal growth and protects the environment.
日粮中的铜和锌添加剂有助于动物的生长发育，但粪便中的重金属会威胁生态环境，而平衡是解决问题的关键。本研究以2000头猪（早期保育猪，9 - 15千克；晚期保育猪，15 - 25千克；生长猪：25 - 60千克）进行试验，分析不同日粮（铜和锌添加剂的梯度剂量）对仔猪和生长猪生长性能、抗氧化性能、免疫功能及粪便重金属排泄的影响。尽管在整个保育 - 生长阶段各处理间平均日增重（ADG）和平均日采食量（ADFI）未观察到显著差异，但日粮中添加适量高剂量的铜和锌对断奶仔猪的抗氧化状态和免疫功能有有益影响。特别是在早期保育阶段，与低铜组（5毫克/千克铜）相比，高铜组（120毫克/千克铜）可显著提高血清中的过氧化物酶（POD）、谷胱甘肽过氧化物酶（GSH - PX）、总抗氧化能力（T - AOC）、过氧化氢酶（CAT）和铜/锌超氧化物歧化酶（Cu/Zn - SOD）、皮质醇。此外，日粮中添加锌和铜不仅增加了血清中相应微量元素的浓度，还影响了血清中其他微量元素的浓度。日粮中铜和锌含量的降低有助于减少粪便中的铜和锌含量。总之，我们为断奶仔猪和生长猪制定了铜和锌的互利剂量（9 - 15千克：5毫克/千克铜和50毫克/千克锌；15 - 25千克：4毫克/千克铜和50毫克/千克锌；25 - 60千克：4毫克/千克铜和10毫克/千克锌），这将有助于确保动物健康生长并减少环境重金属残留。要点：本研究制定了猪日粮中铜和锌的互利剂量，促进动物生长并保护环境。
