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黄韧带骨化症所致胸段脊髓病:两种不同手术减压技术后的手术治疗及长期疗效

Thoracic Myelopathy in Ossified Ligamentum Flavum: Surgical Management and Long-Term Outcome Following 2 Different Techniques of Surgical Decompression.

作者信息

Bagga Rajdeep Singh, Shetty Ajoy P, Viswanathan Vibhu Krishnan, Reddy Gurijala Jyotheswara, Kanna Rishi Mukesh, Rajasekaran S

机构信息

Department of Spine Surgery, Ganga Hospital, Coimbatore, India.

出版信息

Global Spine J. 2023 Apr;13(3):659-667. doi: 10.1177/21925682211003061. Epub 2021 Apr 12.

DOI:10.1177/21925682211003061
PMID:33840238
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10240582/
Abstract

STUDY DESIGN

Retrospective cohort study.

OBJECTIVE

Thoracic ossified ligamentum flavum (TOLF) has been reported to present with varying degrees of neuro-deficit and multiple factors have been purported to affect its outcome. Purpose of study was to analyze factors affecting outcome and impact of ultrasonic osteotome (UO).

METHODS

We retrospectively reviewed patients treated for thoracic myelopathy secondary to OLF between 2010 and 2017. 77 patients with complete clinico-radiological records and 2 years follow-up were included. Initial 45 patients, conventional high-speed burr (HSB-group A) was used for decompression. In others, UO was used in combination with HSB (group B). Myelopathy was graded using modified Japanese orthopaedic association grading pre-operatively and each postoperative visit. At final follow-up, recovery rate was calculated. Radiological details including location, morphology, dural ossification, signal change and spinal ossifications were recorded.

RESULTS

Mean mJOA at presentation and final follow-up were 4.3±1.8 and 7.6±1.9 respectively (p = 0.001). HRR was 49.9±23 at final follow-up. A significant reduction in dural tear (12.5%; 29%) and surgical time (125.8±49.5; 189.4±52.5) were observed in group B (p = 0.00). However, there was no statistically significant difference (p = 0.18) in recovery rates between groups A (44.8±26.1) and B (52.8±24.3). Symptom duration (p = 0.00), severity of myelopathy (p = 0.04) and cord signal changes on MRI (p = 0.02) were important predictors of outcome.

CONCLUSION

Use of UO significantly reduced operative time and dural tears, although resulted in similar recovery rate as compared with HSB. Pre-operative severity of myelopathy, symptom duration and presence of cord signal change were the most significant predictors of outcome.

摘要

研究设计

回顾性队列研究。

目的

据报道,胸椎黄韧带骨化(TOLF)会出现不同程度的神经功能缺损,并且有多种因素被认为会影响其治疗结果。本研究的目的是分析影响治疗结果的因素以及超声骨刀(UO)的作用。

方法

我们回顾性分析了2010年至2017年间因黄韧带骨化继发胸椎脊髓病而接受治疗的患者。纳入了77例具有完整临床和放射学记录且随访2年的患者。最初的45例患者采用传统高速磨钻(HSB组A)进行减压。其他患者则采用超声骨刀联合高速磨钻(B组)。术前及术后每次随访时,采用改良日本骨科协会分级对脊髓病进行分级。在最后一次随访时,计算恢复率。记录包括病变位置、形态、硬脊膜骨化、信号改变和脊柱骨化等放射学细节。

结果

就诊时和最后一次随访时的平均改良日本骨科协会评分分别为4.3±1.8和7.6±1.9(p = 0.001)。最后一次随访时的HRR为49.9±23。B组硬脊膜撕裂(12.5%;29%)和手术时间(125.8±49.5;189.4±52.5)显著减少(p = 0.00)。然而,A组(44.8±26.1)和B组(52.8±24.3)之间的恢复率无统计学显著差异(p = 0.18)。症状持续时间(p = 0.00)、脊髓病严重程度(p = 0.04)和MRI上脊髓信号改变(p = 0.02)是治疗结果的重要预测因素。

结论

使用超声骨刀可显著缩短手术时间和减少硬脊膜撕裂,尽管与高速磨钻相比恢复率相似。术前脊髓病的严重程度、症状持续时间和脊髓信号改变的存在是治疗结果的最重要预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1722/10240582/675e08827a7c/10.1177_21925682211003061-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1722/10240582/80c0e6205c9c/10.1177_21925682211003061-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1722/10240582/fa5449f2bacb/10.1177_21925682211003061-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1722/10240582/451302010e55/10.1177_21925682211003061-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1722/10240582/675e08827a7c/10.1177_21925682211003061-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1722/10240582/80c0e6205c9c/10.1177_21925682211003061-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1722/10240582/fa5449f2bacb/10.1177_21925682211003061-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1722/10240582/451302010e55/10.1177_21925682211003061-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1722/10240582/675e08827a7c/10.1177_21925682211003061-fig4.jpg

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