Department of Critical Care Medicine, the 908th Hospital of Joint Logistics Support Forces of Chinese PLA, Nanchang, 330002, China.
Department of Neurosurgery, the 904th Hospital of Joint Logistics Support Forces of Chinese PLA, Wuxi, 214044, Jiangsu, China.
Mil Med Res. 2021 Apr 12;8(1):25. doi: 10.1186/s40779-021-00317-4.
Trauma-induced coagulopathy (TIC) is caused by post-traumatic tissue injury and manifests as hypercoagulability that leads to thromboembolism or hypocoagulability that leads to uncontrollable massive hemorrhage. Previous studies on TIC have mainly focused on hemorrhagic coagulopathy caused by the hypocoagulable phenotype of TIC, while recent studies have found that trauma-induced hypercoagulopathy can occur in as many as 22.2-85.1% of trauma patients, in whom it can increase the risk of thrombotic events and mortality by 2- to 4-fold. Therefore, the Chinese People's Liberation Army Professional Committee of Critical Care Medicine and the Chinese Society of Thrombosis, Hemostasis and Critical Care, Chinese Medicine Education Association jointly formulated this Chinese Expert Consensus comprising 15 recommendations for the definition, pathophysiological mechanism, assessment, prevention, and treatment of trauma-induced hypercoagulopathy.
创伤诱导性凝血病（TIC）由创伤后组织损伤引起，表现为高凝状态导致血栓栓塞，或低凝状态导致无法控制的大出血。先前关于 TIC 的研究主要集中在 TIC 的低凝表型引起的出血性凝血病上，而最近的研究发现，多达 22.2-85.1%的创伤患者会发生创伤诱导性高凝血症，这会使血栓事件和死亡率增加 2-4 倍。因此，中国人民解放军重症医学专业委员会和中国血栓止血与重症医学、中医药教育协会共同制定了这份中国专家共识，包括 15 条关于创伤诱导性高凝血症的定义、病理生理机制、评估、预防和治疗的建议。
