Pharmacy Systems, Outcomes, and Policy, University of Illinois at Chicago College of Pharmacy, Chicago, Illinois, USA.
Department of Pharmacy Practice, University of Illinois at Chicago College of Pharmacy, Chicago, Illinois, USA.
Value Health. 2021 Apr;24(4):522-529. doi: 10.1016/j.jval.2020.10.008. Epub 2021 Jan 24.
Uncontrolled hypertension is a common cause of cardiovascular disease, which is the deadliest and costliest chronic disease in the United States. Pharmacists are an accessible community healthcare resource and are equipped with clinical skills to improve the management of hypertension through medication therapy management (MTM). Nevertheless, current reimbursement models do not incentivize pharmacists to provide clinical services. We aim to investigate the cost-effectiveness of a pharmacist-led comprehensive MTM clinic compared with no clinic for 10-year primary prevention of stroke and cardiovascular disease events in patients with hypertension.
We built a semi-Markov model to evaluate the clinical and economic consequences of an MTM clinic compared with no MTM clinic, from the payer perspective. The model was populated with data from a recently published controlled observational study investigating the effectiveness of an MTM clinic. Methodology was guided using recommendations from the Second Panel on Cost-Effectiveness in Health and Medicine, including appropriate sensitivity analyses.
Compared with no MTM clinic, the MTM clinic was cost-effective with an incremental cost-effectiveness ratio of $38 798 per quality-adjusted life year (QALY) gained. The incremental net monetary benefit was $993 294 considering a willingness-to-pay threshold of $100 000 per QALY. Health-benefit benchmarks at $100 000 per QALY and $150 000 per QALY translate to a 95% and 170% increase from current reimbursement rates for MTM services.
Our model shows current reimbursement rates for pharmacist-led MTM services may undervalue the benefit realized by US payers. New reimbursement models are needed to allow pharmacists to offer cost-effective clinical services.
未控制的高血压是心血管疾病的常见病因,而心血管疾病是美国最致命和最昂贵的慢性病。药剂师是一种可及的社区医疗资源,他们具备临床技能,可通过药物治疗管理(MTM)改善高血压的管理。然而,当前的报销模式并没有激励药剂师提供临床服务。我们旨在研究与没有 MTM 诊所相比,药剂师主导的综合 MTM 诊所是否能更经济有效地预防高血压患者 10 年内发生中风和心血管疾病事件。
我们构建了一个半马尔可夫模型,从支付者的角度评估 MTM 诊所与没有 MTM 诊所相比的临床和经济后果。该模型使用最近发表的一项关于 MTM 诊所有效性的对照观察研究的数据进行填充。该方法遵循第二版健康与医疗保健成本效益建议,包括适当的敏感性分析。
与没有 MTM 诊所相比,MTM 诊所具有成本效益,增量成本效益比为每获得一个质量调整生命年(QALY)增加 38798 美元。考虑到愿意支付 10 万美元/QALY 的意愿支付阈值,增量净货币收益为 993294 美元。在 10 万美元/QALY 和 15 万美元/QALY 的健康效益基准下,MTM 服务的现行报销率分别提高了 95%和 170%。
我们的模型表明,当前对药剂师主导的 MTM 服务的报销率可能低估了美国支付者实现的收益。需要新的报销模式,使药剂师能够提供具有成本效益的临床服务。