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阿替利珠单抗、贝伐珠单抗、卡铂和紫杉醇联合治疗同步原发性肺腺癌和肝细胞癌取得成功。

Synchronous Primary Lung Adenocarcinoma and Hepatocellular Carcinoma Successfully Treated with a Combination of Atezolizumab, Bevacizumab, Carboplatin, and Paclitaxel.

机构信息

Department of Respiratory Medicine, Kitasato University Kitasato Institute Hospital, Japan.

Department of Pathology, Kitasato University Kitasato Institute Hospital, Japan.

出版信息

Intern Med. 2021 Oct 15;60(20):3273-3277. doi: 10.2169/internalmedicine.6442-20. Epub 2021 Apr 12.

Abstract

Chemotherapy for multiple primary malignancies is challenging. We herein report a case of synchronous primary lung adenocarcinoma and hepatocellular carcinoma (HCC). A 72-year-old man was admitted for the evaluation of an abnormal shadow on his lung. Computed tomography revealed a lung nodule in the right upper lobe and multiple liver masses. He was diagnosed with synchronous primary lung adenocarcinoma and HCC. Atezolizumab, bevacizumab, carboplatin, and paclitaxel (ABCP) chemotherapy was efficacious for both tumors. ABCP chemotherapy may be a potential treatment option for synchronous primary lung adenocarcinoma and HCC.

摘要

多原发恶性肿瘤的化疗具有挑战性。本文报告了 1 例同时性原发性肺腺癌和肝细胞癌(HCC)病例。1 例 72 岁男性因肺部阴影就诊。胸部 CT 显示右上肺结节和多个肝肿块。诊断为同时性原发性肺腺癌和 HCC。阿替利珠单抗、贝伐珠单抗、卡铂和紫杉醇(ABCP)化疗对两种肿瘤均有效。ABCP 化疗可能是同时性原发性肺腺癌和 HCC 的潜在治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe52/8580750/bf149ac52863/1349-7235-60-3273-g001.jpg

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