氧分压指导下的低剂量氧疗治疗肠气囊肿症以预防间质性肺炎急性加重。

Department of Respiratory Medicine, Okayama City Hospital, Japan.

Department of Allergy and Respiratory Medicine, National Hospital Organization, Minami Okayama Medical Center, Japan.

Intern Med. 2021 Oct 1;60(19):3101-3105. doi: 10.2169/internalmedicine.7064-21. Epub 2021 Apr 12.

We herein report the first case of low-dose oxygen therapy for pneumatosis cystoides intestinalis (PCI) using PaO as a therapeutic index to prevent acute exacerbation of interstitial pneumonia. An 86-year-old man was admitted to our hospital with abdominal distension. PCI was diagnosed by abdominal computed tomography. Low-dose oxygen therapy was started to avoid acute exacerbation of interstitial pneumonia. The oxygen dose was adjusted so that the PaO value was approximately 100 mmHg. After seven days of treatment, the colon gas had disappeared, and no acute exacerbation of interstitial pneumonia was observed. A PaO value around 100 mmHg is effective for PCI without inducing acute exacerbation of interstitial pneumonia.

我们在此报告首例使用 PaO 作为治疗指数的低剂量氧疗治疗肠气囊肿症（PCI），以预防间质性肺炎急性加重的病例。一名 86 岁男性因腹胀入住我院。腹部 CT 诊断为 PCI。开始低剂量氧疗以避免间质性肺炎急性加重。调整吸氧剂量，使 PaO 值约为 100mmHg。治疗 7 天后，结肠气体消失，未观察到间质性肺炎急性加重。PaO 值在 100mmHg 左右对 PCI 有效，且不会诱发间质性肺炎急性加重。