Ridder Mark P, Paladino Katie D, Lowe John J, Rupp Mark E
Division of Infectious Disease, University of Nebraska Medical Center, 985400 Nebraska Medical Center, Omaha, NE 68198-5400 USA.
Department of Enterprise Quality and Outcomes, Nebraska Medicine, Omaha, NE 68198 USA.
Curr Treat Options Infect Dis. 2021;13(2):35-46. doi: 10.1007/s40506-021-00247-8. Epub 2021 Apr 6.
Prior outbreaks of respiratory viruses have demonstrated the need for adequate personal protective equipment (PPE) for healthcare workers, particularly filtering facepiece respirators (FFR). Due to shortfalls of PPE during the SARS CoV-2 pandemic, the need for FFR decontamination and reuse (FFR-DR) strategies is paramount. This paper aims to discuss primary decontamination strategies, with an in-depth analysis of ultraviolet germicidal irradiation (UVGI), arriving at the decontamination strategy utilized at the Nebraska Medical Center (NMC).
Review of the primary literature in regard to FFR-DR as well as a synopsis of the current protocol for FFR-DR at NMC.
UVGI demonstrates effective decontamination of multiple pathogens-including several human respiratory viruses-while maintaining mask integrity and filtering capacity. UVGI was associated with degradation of strap integrity at higher doses than that utilized for decontamination or with reuse beyond 20 times.
UVGI effectively decontaminates N95 FFRs without significant reduction to fit or strap integrity and can be employed as a strategy for FFR-DR in times of emergency.
既往呼吸道病毒爆发表明医护人员需要充足的个人防护装备（PPE），尤其是过滤式面罩呼吸器（FFR）。由于严重急性呼吸综合征冠状病毒2（SARS-CoV-2）大流行期间PPE短缺，FFR去污和再利用（FFR-DR）策略至关重要。本文旨在讨论主要的去污策略，并深入分析紫外线杀菌照射（UVGI），得出内布拉斯加医学中心（NMC）采用的去污策略。
回顾关于FFR-DR的主要文献以及NMC当前FFR-DR方案的概要。
UVGI能有效对多种病原体进行去污，包括几种人类呼吸道病毒，同时保持口罩的完整性和过滤能力。在高于去污所用剂量或超过20次重复使用时，UVGI与系带完整性下降有关。
UVGI能有效对N95 FFR进行去污，而不会显著降低贴合度或系带完整性，在紧急情况下可作为FFR-DR的一种策略。
