[Role of the paraventricular nuclei of the hypothalamus in the development of cold adaptation in albino rats].

The role of paraventricular hypothalamic nuclei (PVN) in the development of cold adaptation was studied in chronic experiments on white rats. Animals with the PVN lesions revealed a low resistance against cooling, a small increase of brown adipose tissue mass and no calorigenic effect of noradrenaline after long-lasting cold exposure. The data obtained suggest that the PVN lesions delayed the development of specific mechanisms of adaptation to low temperature.