Ceriotti Serena, Westerfeld Roxane, Bonilla Alvaro G, Pang Daniel S J
Department of Clinical Sciences, University of Montreal, Saint-Hyacinthe, QC, Canada.
Front Vet Sci. 2021 Mar 26;8:630111. doi: 10.3389/fvets.2021.630111. eCollection 2021.
Based on human surgical guidelines, intravenous antimicrobials are recommended to be administered within 60 min of surgical incision. Achieving this target in horses is reportedly challenging and influenced by hospital policies. The objectives of this study were to evaluate and improve: (1) the timing of antimicrobial administration to surgical incision (tAB-INC), (2) contributions of anesthesia pre-induction (tPRI) and surgical preparation (tPREP) periods to tAB-INC, and the (3) completeness of antimicrobial recording. Two clinical audits were conducted before and after the policy changes (patient preparation and anesthesia record keeping). tPRI, tPREP, and tAB-INC were calculated and compared for elective arthroscopies and emergency laparotomies within and between the audits. The percentage of procedures with a tAB-INC <60 min was calculated. Antimicrobial recording was classified as complete or incomplete. A median tAB-INC <60 min was achieved in laparotomies (audit 1; 45 min, audit 2; 53 min) with a shorter tPREP than arthroscopies ( < 0.0001, both audits). The percentage of procedures with tAB-INC <60 min, tAB-INC, tPRI, and tPREP durations did not improve between the audits. There was a positive correlation between the number of operated joints and tPREP (audit 1, <0.001, = 0.77; audit 2, < 0.001, = 0.59). Between audits, antimicrobial recording significantly improved for elective arthroscopies (82-97%, = 0.008) but not emergency laparotomies (76-88%, = 0.2). Clinical audits successfully quantified the impact of introduced changes and their adherence to antimicrobial prophylaxis guidelines. Antimicrobial recording was improved but further policy changes are required to achieve a tAB-INC <60 min for arthroscopies.
根据人类外科手术指南,建议在手术切口后60分钟内静脉注射抗菌药物。据报道,在马匹中实现这一目标具有挑战性,并且受医院政策影响。本研究的目的是评估并改善:(1)抗菌药物给药至手术切口的时间(tAB-INC),(2)麻醉诱导前(tPRI)和手术准备(tPREP)阶段对tAB-INC的影响,以及(3)抗菌药物记录的完整性。在政策变更(患者准备和麻醉记录保存)前后进行了两次临床审计。计算并比较了审计期间内和审计期间之间择期关节镜检查和急诊剖腹手术的tPRI、tPREP和tAB-INC。计算了tAB-INC<60分钟的手术百分比。抗菌药物记录分为完整或不完整。剖腹手术(审计1;45分钟,审计2;53分钟)实现了tAB-INC<60分钟的中位数,其tPREP比关节镜检查短(两次审计均P<0.0001)。审计期间之间,tAB-INC<60分钟的手术百分比、tAB-INC、tPRI和tPREP持续时间没有改善。手术关节数量与tPREP之间存在正相关(审计1,P<0.001,r = 0.77;审计2,P<0.001,r = 0.59)。审计期间之间,择期关节镜检查的抗菌药物记录显著改善(82-97%,P = 0.008),但急诊剖腹手术没有改善(76-88%,P = 0.2)。临床审计成功量化了引入变更的影响及其对抗菌药物预防指南的遵守情况。抗菌药物记录得到了改善,但需要进一步的政策变更,以使关节镜检查的tAB-INC<60分钟。