Li Gangping, Jin Yu, Bai Tao, Qian Wei, Xie Xiaoping, Hou Xiaohua
Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ann Transl Med. 2021 Mar;9(5):411. doi: 10.21037/atm-20-3699.
Capsule endoscopy for visualization of the entire gastrointestinal tract is a challenge. A second-generation colon capsule endoscopy system (CCE-2) performed well in the colon and small intestine, but its utility in the upper gastrointestinal duct is not clear. We evaluated the use of the CCE-2 in the visualization of the upper gastrointestinal tract.
We performed a retrospective study and further evaluated CCE-2 images using the typical landmarks of esophagus and stomach. The two imagers located at each end of the CCE-2 system were defined as imager1 (green) and imager2 (yellow). Two endoscopists read the images, and they were blinded to the other reader's results. All of the images from the two imagers were separately reviewed.
Images from 127 subjects were analyzed. This study demonstrated the comprehensive visualization of 71.7% of esophageal landmarks and 89.8% of gastric landmarks using the CCE-2. The two CCE-2 imagers were not identical, and the lighter imager (imager2, yellow) was superior to the heavier imager (imager1, green) (78% 33.1%) in the stomach. Compared with the use of one imager, the use of two imagers was superior (two-imager imager1, 89.8% 33.1%; two-imager imager2, 89.8% 78%) in the stomach. Two-imager combination analysis detected a total of 160 positive findings. In contrast, single-imager analysis with imager1 and imager2 detected 133 and 137 findings, respectively. Two-imager combination analysis provided 20.3% and 16.8% more findings than imager1 and imager2, respectively. The two imagers complemented each other to detect more lesions.
The CCE-2 system is feasible for use in the upper gastrointestinal tract and may be considered an optional tool for upper gastrointestinal imaging. This system may represent a good choice for complete gastrointestinal duct screening. Compared with the use of one imager, the two-imager combination provided improved upper gastrointestinal tract mucosal visualization.
使用胶囊内镜对整个胃肠道进行可视化检查具有挑战性。第二代结肠胶囊内镜系统（CCE - 2）在结肠和小肠检查中表现良好，但其在上消化道的应用效果尚不清楚。我们评估了CCE - 2在上消化道可视化检查中的应用。
我们进行了一项回顾性研究，并使用食管和胃的典型标志进一步评估CCE - 2图像。位于CCE - 2系统两端的两个成像器分别定义为成像器1（绿色）和成像器2（黄色）。两位内镜医师阅读图像，且对彼此的结果不知情。对来自两个成像器的所有图像分别进行审查。
分析了127名受试者的图像。本研究表明，使用CCE - 2可全面观察到71.7%的食管标志和89.8%的胃标志。两个CCE - 2成像器有所不同，在胃内，颜色较浅的成像器（成像器2，黄色）优于颜色较深的成像器（成像器1，绿色）（78%对33.1%）。与使用一个成像器相比，使用两个成像器在胃内的观察效果更佳（两个成像器对成像器1，89.8%对33.1%；两个成像器对成像器2，89.8%对78%）。两个成像器联合分析共检测到160个阳性结果。相比之下，成像器1和成像器2单独分析分别检测到133个和137个结果。两个成像器联合分析比成像器1和成像器2分别多检测到20.3%和16.8%的结果。两个成像器相互补充，能检测到更多病变。
CCE - 2系统在上消化道检查中是可行的，可被视为上消化道成像的一种可选工具。该系统可能是全胃肠道筛查的一个不错选择。与使用一个成像器相比，两个成像器联合使用可改善上消化道黏膜的可视化效果。
