Department of Diagnostic Imaging, Sheba Medical Center, Tel Hashomer, Israel.
Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Acta Radiol. 2022 Mar;63(3):387-392. doi: 10.1177/0284185121996270. Epub 2021 Apr 11.
Takayasu arteritis (TA), a systemic large-vessel vasculitis, was reported to have high incidence of spondyloarthropathy.
To evaluate the prevalence of inflammatory sacroiliitis in patients with TA that underwent abdominal/pelvic magnetic resonance imaging (MRI) examinations as part of their vasculitis work-up.
Consecutive abdominal/pelvic MRI examinations of 34 patients with TA fulfilling the 1990 ACR criteria and 34 age- and gender-matched controls performed between 2008 and 2020 were retrospectively reviewed for the presence sacroiliitis. The presence of active and structural lesions was scored twice (with a one-month interval between reads) by one reader. Structural lesions were also evaluated on computed tomography, when available, and correlated to MRI findings. Clinical data were extracted from the patients' clinical files. MRI scores were compared between the study and control groups and correlated with the clinical data.
Sacroiliitis was evident in 11.7% of the TA group examinations compared to 0.3% in the control group ( = 0.6). Participants with TA had significantly more erosions and fat deposition compared to the control group (Study: 0.01/0.03, Control: 0/0, = 0.03/0.003, respectively). However, mean sacroiliitis score was not significantly different (Study: 1.06, Control: 0.78, = 0.015). Of the four patients with TA and sacroiliitis, 3 (75%) had a diagnosis of inflammatory bowel disease (IBD).
Sacroiliitis was detected in 11.7% of abdominal MRI examinations of patients with TA, 75% of which had associated IBD, suggesting that both IBD and sacroiliitis should be routinely screened in the TA population as their presence may influence treatment decisions.
Takayasu 动脉炎（TA）是一种系统性大血管血管炎，据报道其脊柱关节病的发病率很高。
评估作为血管炎检查一部分而接受腹部/骨盆磁共振成像（MRI）检查的 TA 患者中炎症性骶髂关节炎的患病率。
回顾性分析 2008 年至 2020 年间连续进行的 34 例符合 1990 年 ACR 标准的 TA 患者和 34 例年龄和性别匹配的对照者的腹部/骨盆 MRI 检查，以评估骶髂关节炎的存在。一位读者两次对存在的活动性和结构病变进行评分（两次评分间隔一个月）。如果有条件，还会在 CT 上评估结构病变，并与 MRI 结果相关联。从患者的临床档案中提取临床数据。比较研究组和对照组的 MRI 评分，并与临床数据相关联。
TA 组 11.7%的检查存在骶髂关节炎，而对照组为 0.3%（ = 0.6）。与对照组相比，TA 患者的侵蚀和脂肪沉积明显更多（研究组：0.01/0.03，对照组：0/0， = 0.03/0.003）。然而，平均骶髂关节炎评分无显著差异（研究组：1.06，对照组：0.78， = 0.015）。在 4 例有骶髂关节炎的 TA 患者中，有 3 例（75%）患有炎症性肠病（IBD）。
在 TA 患者的腹部 MRI 检查中，11.7%发现骶髂关节炎，其中 75%存在相关的 IBD，这表明在 TA 人群中应常规筛查 IBD 和骶髂关节炎，因为它们的存在可能会影响治疗决策。
