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[慢性肢体缺血的血管内治疗。48例手术经验]

[Endovascular management of chronic limb ischemia. Experience in 48 procedures].

作者信息

Torrealba J Ignacio, Vargas J Francisco, Mariné Leopoldo A, Bergoeing Michel P, Mertens Renato A, Valdés Francisco J

机构信息

Departamento cirugía vascular, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

出版信息

Rev Med Chil. 2020 Dec;148(12):1734-1741. doi: 10.4067/S0034-98872020001201734.

Abstract

BACKGROUND

Chronic limb ischemia can lead to high rates of limb loss and mortality. Open surgery is the gold standard for treatment of distal disease. Endovascular surgery should have less complications with similar outcomes.

AIM

To report a cohort of patients with distal arterial disease treated with endovascular surgery at our institution.

MATERIAL AND METHODS

Review of angioplasty records of patients undergoing distal lower extremity endovascular procedures between 2016 and 2019. Demographics, comorbidities, form of presentation, type of intervention, perioperative complications, and length of stay were analyzed. The primary outcomes were wound healing, reinterventions and freedom from major amputation. Secondary outcomes were overall survival and amputation-free survival.

RESULTS

Forty-eight limbs of 41 patients with a mean age 75 years (78% males) were treated. Ninety-three percent had hypertension, 88% diabetes, 30% chronic kidney disease. 73% presented with major wounds. Plain balloon and drug coated balloon angioplasties were carried out in 65 and 31% of procedures respectively, with no difference in results. In 46% of the cases, only chronic total occlusions were treated. Wound healing was achieved in 85% of procedures and 90% of patients were free from amputation at one year of follow up. Complications were observed in 18% of procedures, perioperative mortality was 2% and one-year survival was 76%.

CONCLUSIONS

Endovascular therapy achieves high rates of wound healing and freedom from amputation with low perioperative mortality and moderate complication rates.

摘要

背景

慢性肢体缺血可导致高截肢率和死亡率。开放手术是治疗远端疾病的金标准。血管腔内手术应具有较少的并发症且疗效相似。

目的

报告在我们机构接受血管腔内手术治疗的远端动脉疾病患者队列。

材料与方法

回顾2016年至2019年间接受下肢远端血管腔内手术患者的血管成形术记录。分析人口统计学、合并症、表现形式、干预类型、围手术期并发症和住院时间。主要结局为伤口愈合、再次干预和免于大截肢。次要结局为总生存率和无截肢生存率。

结果

治疗了41例患者的48条肢体,平均年龄75岁(男性占78%)。93%患有高血压,88%患有糖尿病,30%患有慢性肾病。73%有严重伤口。分别在65%和31%的手术中进行了普通球囊血管成形术和药物涂层球囊血管成形术,结果无差异。46%的病例仅治疗慢性完全闭塞。85%的手术实现了伤口愈合,90%的患者在随访一年时免于截肢。18%的手术观察到并发症,围手术期死亡率为2%,一年生存率为76%。

结论

血管腔内治疗可实现高伤口愈合率和免于截肢,围手术期死亡率低,并发症发生率中等。

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