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[以深静脉血栓形成表现的下腔静脉发育不全。1例报告]

[Inferior vena cava agenesis presenting as deep vein thrombosis. Report of one case].

作者信息

Castro L Fernanda, Zapico Álvaro, Wilhelm Ricardo

机构信息

Hospital San Martín de Quillota, Quillota, Chile.

出版信息

Rev Med Chil. 2020 Dec;148(12):1833-1837. doi: 10.4067/S0034-98872020001201833.

DOI:10.4067/S0034-98872020001201833
PMID:33844751
Abstract

Abnormalities of the inferior vena cava are rare. Its embryological development occurs between the sixth and eighth week of gestation and depends on the persistence or regression of three pairs of veins: the posterior cardinal veins, the subcardinal veins and the supracardinal veins. The type of congenital alteration depends on the moment that embryogenesis is altered. The most frequent clinical presentation is deep vein thrombosis, which occurs mainly in young men. We report a 16-year-old male presenting with edema of the left leg. No risk factor for thrombosis was recorded. A Doppler ultrasound confirmed the presence of a deep femoro-popliteal vein thrombosis. An abdominal CAT scan showed an agenesis of the supra and infra-adrenal inferior vena cava, with multiple collaterals. The study for thrombophilia was negative. The patient was treated with vitamin K antagonists with a good clinical response.

摘要

下腔静脉异常较为罕见。其胚胎发育发生在妊娠的第六至第八周,取决于三对静脉的持续或退化:后主静脉、亚主静脉和上主静脉。先天性改变的类型取决于胚胎发育改变的时刻。最常见的临床表现是深静脉血栓形成,主要发生在年轻男性身上。我们报告一名16岁男性,表现为左腿水肿。未记录到血栓形成的危险因素。多普勒超声证实存在股腘深静脉血栓形成。腹部计算机断层扫描显示肾上腺上下下腔静脉缺如,伴有多处侧支循环。血栓形成倾向的检查结果为阴性。该患者接受了维生素K拮抗剂治疗,临床反应良好。

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