Lijnen P, Hespel P, Fagard R, Lysens R, Vanden Eynde E, Goris M, Goossens W, Lissens W, Amery A
Department of Pathophysiology, Faculty of Medicine, University of Leuven, Belgium.
Int J Sports Med. 1988 Apr;9(2):108-13. doi: 10.1055/s-2007-1024989.
Plasma indicators of muscle cell leakage and of hemolysis were studied in 23 runners before and after a marathon race. Blood samples were drawn from an antecubital vein the morning before the race (baseline), at 3 p.m., i.e., 2 h before the start, on arrival, 12 and 36 h, and 7 days later. Compared with the baseline values, the plasma creatinine phosphokinase MM and MB subfractions, aldolase and glutamicoxaloacetic transaminase activity were increased immediately after the race, rose further 12 h after the marathon, and remained elevated the race, rose further 12 h after the marathon, and remained elevated 36 h and 7 days later. The plasma lactate dehydrogenase activity and myoglobin concentration were increased on arrival and returned to the pre-race activity 7 days after the marathon. Compared with the pre-race values, the plasma haptoglobin concentration was decreased immediately and 12 h after the marathon. Our data show that indicators of muscle cell leakage and of hemolysis in plasma, withdrawn after a marathon race, remained elevated for up to 7 days after the race.
对23名马拉松运动员在比赛前后的血浆中肌肉细胞渗漏和溶血指标进行了研究。在比赛前一天上午（基线）、下午3点（即比赛开始前2小时）、抵达时、赛后12小时、36小时以及7天后，从前臂肘前静脉采集血样。与基线值相比，血浆肌酸磷酸激酶MM和MB亚组分、醛缩酶以及谷草转氨酶活性在比赛后立即升高，马拉松赛后12小时进一步升高，并在赛后36小时和7天仍保持升高。血浆乳酸脱氢酶活性和肌红蛋白浓度在抵达时升高，并在马拉松赛后7天恢复到赛前水平。与赛前值相比，血浆触珠蛋白浓度在马拉松赛后立即和12小时降低。我们的数据表明，马拉松赛后采集的血浆中肌肉细胞渗漏和溶血指标在赛后长达7天仍保持升高。
