La Vecchia C, Pagano R, Negri E, Decarli A
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
Int J Epidemiol. 1988 Mar;17(1):50-5. doi: 10.1093/ije/17.1.50.
The relation between smoking habits and selected chronic diseases was evaluated from the data of the 1983 Italian National Health Survey, based on 72,284 people aged 15 or over randomly selected within strata of geographical area, size of place of residence and of the household in order to be representative of the whole Italian population. The prevalence of all the 19 diseases or groups of diseases considered was elevated among ex-smokers, thus suggesting that the presence of any chronic condition stimulates cessation of smoking. The excess prevalence among ex-smokers was particularly large for myocardial infarction and other heart diseases. Four groups of diseases were positively related with current as well as with past cigarette smoking. These were chronic bronchitis, emphysema of the lung or respiratory insufficiency, gastroduodenal ulcer and varicose veins or haemorrhoids. For all these groups of diseases the relative risks were higher in heavy cigarette smokers. Compared with never smokers, the point estimates for subjects smoking 15 cigarettes per day or more were 2.6 for chronic bronchitis, 1.7 for emphysema of the lung, 2.1 for gastroduodenal ulcer and 1.6 for varicose veins or haemorrhoids. For bronchitis, ulcer and varicose veins or haemorrhoids the relative risks tended to be higher in younger and middle age groups. From these data, it was estimated that in the whole of Italy a total of about 900,000 prevalent cases of chronic bronchitis, 270,000 of emphysema, 610,000 gastroduodenal ulcers and 380,000 varicose veins or haemorrhoids could be associated with cigarette smoking.(ABSTRACT TRUNCATED AT 250 WORDS)
根据1983年意大利全国健康调查的数据,对吸烟习惯与某些慢性病之间的关系进行了评估。该调查基于在地理区域、居住地点规模和家庭规模等分层中随机抽取的72284名15岁及以上的人群,旨在代表整个意大利人口。在所考虑的所有19种疾病或疾病组中,既往吸烟者的患病率均有所升高,这表明任何慢性病的存在都会促使人们戒烟。既往吸烟者中心肌梗死和其他心脏病的患病率尤其高。四组疾病与当前吸烟以及既往吸烟均呈正相关。这些疾病是慢性支气管炎、肺气肿或呼吸功能不全、胃十二指肠溃疡以及静脉曲张或痔疮。对于所有这些疾病组,重度吸烟者的相对风险更高。与从不吸烟者相比,每天吸烟15支及以上者患慢性支气管炎的点估计值为2.6,患肺气肿的为1.7,患胃十二指肠溃疡的为2.1,患静脉曲张或痔疮的为1.6。对于支气管炎、溃疡以及静脉曲张或痔疮,相对风险在年轻和中年人群中往往更高。根据这些数据估计,在整个意大利,约90万例慢性支气管炎、27万例肺气肿、61万例胃十二指肠溃疡以及38万例静脉曲张或痔疮的现患病例可能与吸烟有关。(摘要截选至250词)