Center of Excellence for Advanced Materials Research (CEAMR), King Abdulaziz University, Jeddah, 21589, P.O. Box 80203, Saudi Arabia.
Department of Chemistry, Faculty of Science, King Abdulaziz University, Jeddah, 21589, P.O. Box 80203, Saudi Arabia.
Chem Asian J. 2021 Jun 1;16(11):1475-1485. doi: 10.1002/asia.202100250. Epub 2021 May 5.
Here, an electrochemical detection approach (differential pulse voltammetry) was employed to develop a 2-nitrophenol (2-NP) sensor probe using a glassy carbon electrode (GCE) coated by wet-chemically synthesized nanorods (NRs) of BaO. The prepared BaO NRs were characterized by field-emission scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDS), X-ray photoelectron spectroscopy (XPS) and powder X-ray diffraction (XRD) analysis. The peak currents by differential pulse voltammetric (DPV) analysis of 2-NP are plotted against the concentration to obtain the calibration curve of the 2-NP detection. It was found to be linear from 1.5 to 9.0 μM, defined as the dynamic range (LDR) for 2-NP detection in phosphate buffer solution. The sensor sensitivity was calculated from the slope of LDR by considering the active surface area of NRs coated on GCE (0.0316 cm ) and found as 17.6 μAμM cm . The limit of detection (LOD) was calculated as 0.50±0.025 μM from the signal/noise (S/N) ratio of 3. Moreover, the sensor analytical parameters such as reproducibility, long-term performing ability (stability), response time and validity in real environmental samples were found acceptable and to give satisfactory results. The development of a nanomaterial-based electrochemical chemical sensor might be an effective approach to sensor technology to detect carcinogenic and hazardous toxins for environmental safety and healthcare fields in a broad scale.
在这里，我们采用电化学检测方法（差分脉冲伏安法），在玻碳电极（GCE）上涂覆湿化学合成的 BaO 纳米棒（NRs），开发出一种 2-硝基苯酚（2-NP）传感器探针。通过场发射扫描电子显微镜（FESEM）、能谱（EDS）、X 射线光电子能谱（XPS）和粉末 X 射线衍射（XRD）分析对制备的 BaO NRs 进行了表征。通过差分脉冲伏安（DPV）分析对 2-NP 的峰值电流进行了测定，绘制出与浓度的关系曲线，得到 2-NP 检测的校准曲线。结果表明，在磷酸盐缓冲溶液中，2-NP 的检测范围为 1.5 至 9.0 μM，定义为动态范围（LDR）。通过考虑涂覆在 GCE 上的 NRs 的有效表面积（0.0316 cm ），从 LDR 的斜率计算出传感器的灵敏度，发现其值为 17.6 μAμM cm 。根据信噪比（S/N）为 3 计算出的检测限（LOD）为 0.50±0.025 μM。此外，该传感器在实际环境样品中的分析参数，如重现性、长期性能（稳定性）、响应时间和有效性等，均表现出良好的接受程度和令人满意的结果。基于纳米材料的电化学化学传感器的开发可能是一种有效的传感器技术，可广泛应用于环境安全和医疗保健领域，用于检测致癌和有害毒素。
