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本文引用的文献

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Cancer. 2021 Jan 1;127(1):67-73. doi: 10.1002/cncr.33202. Epub 2020 Sep 28.
2
Living with a Hope of Survival Is Challenged by a Lack of Clinical Evidence: An Interview Study among Cancer Patients Using Cannabis-Based Medicine.生存希望受到缺乏临床证据的挑战:使用大麻类药物的癌症患者的访谈研究。
J Palliat Med. 2020 Aug;23(8):1090-1093. doi: 10.1089/jpm.2019.0298. Epub 2019 Nov 11.
3
Opportunities for cannabis in supportive care in cancer.大麻在癌症支持性护理中的应用机遇。
Ther Adv Med Oncol. 2019 Aug 1;11:1758835919866362. doi: 10.1177/1758835919866362. eCollection 2019.
4
Medical Oncologists' Views on the Utility of Medical Marijuana Across the Cancer Trajectory.肿瘤内科医生对医用大麻在癌症病程中的效用的看法。
J Pain Symptom Manage. 2019 Jun;57(6):e1-e4. doi: 10.1016/j.jpainsymman.2019.02.001. Epub 2019 Feb 19.
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Sleepless from the Get Go: Sleep Problems Prior to Initiating Cancer Treatment.从一开始就失眠:癌症治疗开始前的睡眠问题
Int J Behav Med. 2018 Oct;25(5):502-516. doi: 10.1007/s12529-018-9715-2.
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Cannabis use among patients at a comprehensive cancer center in a state with legalized medicinal and recreational use.在一个医用大麻和娱乐用大麻均合法化的州,一家综合癌症中心的患者使用大麻的情况。
Cancer. 2017 Nov 15;123(22):4488-4497. doi: 10.1002/cncr.30879. Epub 2017 Sep 25.
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Code Saturation Versus Meaning Saturation: How Many Interviews Are Enough?代码饱和度与意义饱和度:多少次访谈才算足够?
Qual Health Res. 2017 Mar;27(4):591-608. doi: 10.1177/1049732316665344. Epub 2016 Sep 26.
8
Evaluation and treatment of insomnia in adult cancer survivorship programs.成人癌症幸存者项目中失眠的评估与治疗
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9
Cannabis species and cannabinoid concentration preference among sleep-disturbed medicinal cannabis users.睡眠障碍的药用大麻使用者对大麻品种和大麻素浓度的偏好
Addict Behav. 2015 Nov;50:178-81. doi: 10.1016/j.addbeh.2015.06.032. Epub 2015 Jun 23.
10
Insomnia in adult survivors of childhood cancer: a report from project REACH.儿童癌症成年幸存者的失眠:REACH项目报告
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癌症患者对使用医用大麻改善睡眠的态度。

Cancer patient's attitudes of using medicinal cannabis for sleep.

机构信息

Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, MA, USA.

Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA.

出版信息

J Psychosoc Oncol. 2022;40(3):397-403. doi: 10.1080/07347332.2021.1910396. Epub 2021 Apr 13.

DOI:10.1080/07347332.2021.1910396
PMID:33847549
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8511353/
Abstract

PURPOSE

Poor sleep is one of the most common side effects of cancer treatment. One increasingly popular approach to manage side effects of cancer treatment is use of medicinal cannabis (MC).

DESIGN

Cancer patients using MC participated in semi-structured interviews to assess their experiences with MC (n = 24). A multi-stage thematic analysis was applied to interview transcripts. Themes related to use of MC for sleep were extracted.

FINDINGS

The majority reported MC use for sleep. These participants reported that MC improved sleep initiation and continuity, resulted in decreased use of sleep medications, and that improved sleep led to better health. No participant reported MC was ineffectual for sleep or caused undesirable side effects when used for sleep.

CONCLUSIONS

Cancer patients often utilize MC to specifically manage poor sleep. There is a need for rigorous studies assessing prevalence of use for this indication and clinical trials to assess comparative efficacy and safety.

摘要

目的

睡眠不佳是癌症治疗最常见的副作用之一。一种越来越受欢迎的治疗癌症副作用的方法是使用药用大麻(MC)。

设计

使用 MC 的癌症患者参与了半结构化访谈,以评估他们使用 MC 的体验(n=24)。对访谈记录应用了多阶段主题分析。提取了与 MC 用于睡眠相关的主题。

结果

大多数患者报告称 MC 可用于改善睡眠。这些参与者报告说,MC 改善了睡眠的开始和连续性,减少了睡眠药物的使用,改善了睡眠,从而改善了健康状况。没有参与者报告 MC 对睡眠无效或在用于睡眠时产生不良副作用。

结论

癌症患者经常使用 MC 来专门治疗睡眠不佳。需要进行严格的研究来评估这种适应症的使用频率,并进行临床试验以评估比较疗效和安全性。