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在进展期胰腺癌胰十二指肠切除术中使用右胃网膜动脉进行肝动脉切除和重建。

Hepatic artery resection and reconstruction using the right gastroepiploic artery during pancreaticoduodenectomy in advanced pancreatic cancer.

机构信息

Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan.

Department of Diagnostic Pathology, Yamaguchi University Hospital, Ube, Yamaguchi, 755-8505, Japan.

出版信息

Langenbecks Arch Surg. 2021 Sep;406(6):2075-2080. doi: 10.1007/s00423-021-02120-0. Epub 2021 Apr 13.

Abstract

PURPOSE

Surgical resection is the only curative treatment for pancreatic cancer. Arterial resection and reconstruction during pancreaticoduodenectomy for advanced pancreatic cancer remain controversial due to a high rate of complications.

METHODS

We report two cases of pancreatic cancer with hepatic artery resection and reconstruction using the right gastroepiploic artery during pancreaticoduodenectomy after neoadjuvant therapy.

RESULTS

The patients underwent pancreaticoduodenectomy with resection of the right hepatic and common hepatic arteries. Achieving direct anastomosis was difficult; therefore, we planned hepatic artery reconstruction using the right gastroepiploic artery. We performed the reconstruction using an interrupted suture with end-to-end anastomosis. The first patient developed a postoperative pancreatic fistula, while the postoperative course of the second patient was uneventful. However, there were no adverse events related to the arterial reconstruction. R0 resection was achieved, and postoperative computed tomography revealed good patency of the reconstructed artery.

CONCLUSION

Hepatic artery reconstruction using the right gastroepiploic artery in pancreatic cancer might be technically safe and might become one of the alternative options.

摘要

目的

手术切除是治疗胰腺癌的唯一方法。在进展期胰腺癌行胰十二指肠切除术时,由于并发症发生率较高,肝动脉切除和重建仍存在争议。

方法

我们报告了两例新辅助治疗后行胰十二指肠切除术的胰腺癌患者,术中采用右胃网膜动脉行肝总动脉和肝固有动脉切除和重建。

结果

两例患者均行胰十二指肠切除术,切除右肝动脉和肝总动脉。由于直接吻合困难,我们计划使用右胃网膜动脉进行肝动脉重建。我们采用端对端吻合的间断缝合进行重建。第一例患者术后发生胰瘘,第二例患者术后无并发症。但是,没有与动脉重建相关的不良事件。达到了 R0 切除,术后 CT 显示重建动脉通畅良好。

结论

在胰腺癌中使用右胃网膜动脉进行肝动脉重建可能在技术上是安全的,并且可能成为一种替代选择。

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