El Abbadi Sam, Susok Laura, Stockfleth Egger, Bechara Falk Georges, Gambichler Thilo, Herbrandt Swetlana, Goldschmidtböing Lisa, Sand Michael
Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital OWL, Campus Klinikum Bielefeld Center, Bielefeld, Germany.
Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Bochum, Germany.
Dermatol Ther (Heidelb). 2021 Jun;11(3):929-940. doi: 10.1007/s13555-021-00522-y. Epub 2021 Apr 13.
Few studies have evaluated patient-reported outcome measures and the effect of patient educational materials in German patients with skin cancer. We conducted a prospective study to measure the impact of treatment on health-related quality of life in German patients with skin cancer, identify variables that may contribute to changes in health-related quality of life, and evaluate the effect of providing additional information through a patient education brochure.
A total of 461 patients diagnosed with actinic keratosis, nonmetastatic nonmelanoma skin cancer, melanoma in situ, or nonmetastatic cutaneous melanoma treated between August 2018 and July 2020 were included. Ninety-seven patients were randomly selected to receive an additional patient education brochure ("Hautkrebs"). The patients completed a Skin Cancer Quality of Life Index Tool (n = 324) or a Skin Cancer Index Questionnaire (n = 137) 1 week after surgical treatment.
Ninety-seven patients were provided an additional patient education brochure. We found statistical correlation between sociodemographic factors (young age and female gender) and the location of the skin cancer (head and face) and impairment of health-related quality of life in patients with skin cancer (p < 0.05). Moreover, we found that patients who were presented a brochure showed significantly higher awareness concerning direct sun exposure (p < 0.05).
Impaired health-related quality of life is correlated with a patient with skin cancer's age, gender, and the location of the lesion. Physicians should consider these factors in clinical practice and advocate the use of patient education brochures as effective assets in preventing the reoccurrence of skin cancer.
很少有研究评估德国皮肤癌患者的患者报告结局指标以及患者教育材料的效果。我们进行了一项前瞻性研究，以衡量治疗对德国皮肤癌患者健康相关生活质量的影响，确定可能导致健康相关生活质量变化的变量，并评估通过患者教育手册提供额外信息的效果。
纳入2018年8月至2020年7月期间接受治疗的461例诊断为光化性角化病、非转移性非黑素瘤皮肤癌、原位黑素瘤或非转移性皮肤黑素瘤的患者。随机选择97例患者接受额外的患者教育手册（“皮肤癌”）。患者在手术治疗1周后完成皮肤癌生活质量指数工具（n = 324）或皮肤癌指数问卷（n = 137）。
97例患者获得了额外的患者教育手册。我们发现社会人口统计学因素（年轻和女性）与皮肤癌的位置（头面部）以及皮肤癌患者健康相关生活质量受损之间存在统计学相关性（p < 0.05）。此外，我们发现收到手册的患者对直接日晒的认识明显更高（p < 0.05）。
健康相关生活质量受损与皮肤癌患者的年龄、性别和病变位置相关。医生在临床实践中应考虑这些因素，并提倡使用患者教育手册作为预防皮肤癌复发的有效手段。
